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CD14 Protein (CD14) (AA 20-345, Membrane-Bound) (GST tag)

CD14 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 90 % SDS
N° du produit ABIN5709227
  • Antigène Voir toutes CD14 Protéines
    CD14
    Type de proteíne
    Recombinant
    Attributs du protein
    Membrane-Bound, AA 20-345
    Origine
    • 20
    • 5
    • 4
    • 1
    • 1
    • 1
    Humain
    Source
    • 15
    • 8
    • 3
    • 2
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification/Conjugué
    Cette CD14 protéine est marqué à la GST tag.
    Application
    SDS-PAGE (SDS)
    Séquence
    TTPEPCELDD EDFRCVCNFS EPQPDWSEAF QCVSAVEVEI HAGGLNLEPF LKRVDADADP RQYADTVKAL RVRRLTVGAA QVPAQLLVGA LRVLAYSRLK ELTLEDLKIT GTMPPLPLEA TGLALSSLRL RNVSWATGRS WLAELQQWLK PGLKVLSIAQ AHSPAFSCEQ VRAFPALTSL DLSDNPGLGE RGLMAALCPH KFPAIQNLAL RNTGMETPTG VCAALAAAGV QPHSLDLSHN SLRATVNPSA PRCMWSSALN SLNLSFAGLE QVPKGLPAKL RVLDLSCNRL NRAPQPDELP EVDNLTLDGN PFLVPGTALP HEGSMN
    Purification
    SDS-PAGE
    Pureté
    > 90 %
    Top Product
    Discover our top product CD14 Protéine
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.1-2 mg/mL
    Buffer
    20 mM Tris-HCl based buffer, pH 8.0
    Stock
    -80 °C,4 °C,-20 °C
    Stockage commentaire
    Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Antigène
    CD14
    Autre désignation
    CD14 (CD14 Produits)
    Synonymes
    CD14 molecule Protein, CD14 antigen Protein, CD14 Protein, Cd14 Protein
    Sujet
    In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the MD-2/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Up-regulates cell surface molecules, including adhesion molecules.
    Poids moléculaire
    62.5 kDa
    UniProt
    P08571
    Pathways
    Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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