FGF19 Protein (AA 32-216, partial) (GST tag)

N° du produit ABIN5712472

Détail du produit

Antigène: FGF19 (Fibroblast Growth Factor 19 (FGF19))

Type de proteíne: Recombinant

Attributs du protein: AA 32-216, partial

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette FGF19 protéine est marqué à la GST tag.

Application: SDS-PAGE (SDS)

Séquence: PHVHYGWGDP IRLRHLYTSG PHGLSSCFLR IRADGVVDCA RGQSAHSLLE IKAVALRTVA IKGVHSVRYL CMGADGKMQG LLQYSEEDCA FEEEIRPDGY NVYRSEKHRL PVSLSSAKQR QLYKNRGFLP LSHFLPMLPM VPEEPEDLRG HLESDMFSSP LETDSMDPFG LVTGLEAVRS PSFEK

Purification: SDS-PAGE

Pureté: > 90 %

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Stock: -80 °C,4 °C,-20 °C

Stockage commentaire: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Détail du antigène

Antigène: FGF19 (Fibroblast Growth Factor 19 (FGF19))

Autre désignation: FGF19 (FGF19 Produits)

Synonymes: FGF-19 Protein, Fgf15 Protein, fibroblast growth factor 19 Protein, FGF19 Protein, Fgf19 Protein, fgf19 Protein

Sujet: Involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. Stimulates glucose uptake in adipocytes. Activity requires the presence of KLB and FGFR4.

Poids moléculaire: 48.2 kDa

UniProt: O95750

Pathways: Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway