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RAD23A Protein (AA 1-363, full length) (His tag)

RAD23A Origine: Humain Hôte: Levure Recombinant > 90 % SDS
N° du produit ABIN5713780
  • Antigène Voir toutes RAD23A Protéines
    RAD23A (RAD23 Homolog A (RAD23A))
    Type de proteíne
    Recombinant
    Attributs du protein
    full length, AA 1-363
    Origine
    • 6
    • 1
    • 1
    Humain
    Source
    • 2
    • 2
    • 2
    • 1
    • 1
    Levure
    Purification/Conjugué
    Cette RAD23A protéine est marqué à la His tag.
    Application
    SDS-PAGE (SDS)
    Séquence
    MAVTITLKTL QQQTFKIRME PDETVKVLKE KIEAEKGRDA FPVAGQKLIY AGKILSDDVP IRDYRIDEKN FVVVMVTKTK AGQGTSAPPE ASPTAAPESS TSFPPAPTSG MSHPPPAARE DKSPSEESAP TTSPESVSGS VPSSGSSGRE EDAASTLVTG SEYETMLTEI MSMGYERERV VAALRASYNN PHRAVEYLLT GIPGSPEPEH GSVQESQVSE QPATEAAGEN PLEFLRDQPQ FQNMRQVIQQ NPALLPALLQ QLGQENPQLL QQISRHQEQF IQMLNEPPGE LADISDVEGE VGAIGEEAPQ MNYIQVTPQE KEAIERLKAL GFPESLVIQA YFACEKNENL AANFLLSQNF DDE
    Purification
    SDS-PAGE
    Pureté
    > 90 %
    Top Product
    Discover our top product RAD23A Protéine
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.1-2 mg/mL
    Buffer
    20 mM Tris-HCl based buffer, pH 8.0
    Stock
    -80 °C,4 °C,-20 °C
    Stockage commentaire
    Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Antigène
    RAD23A (RAD23 Homolog A (RAD23A))
    Autre désignation
    RD23A (RAD23A Produits)
    Synonymes
    rad23a Protein, wu:fe11h06 Protein, zgc:92001 Protein, RAD23A Protein, HHR23A Protein, HR23A Protein, 2310040P19Rik Protein, AL024030 Protein, mHR23A Protein, RAD23 homolog A, nucleotide excision repair protein a Protein, RAD23 homolog A, nucleotide excision repair protein Protein, rad23aa Protein, RAD23A Protein, Rad23a Protein
    Sujet
    Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Binds to 'Lys-48'-linked polyubiquitin chains in a length-dependent manner and with a lower affinity to 'Lys-63'-linked polyubiquitin chains. Proposed to be capable to bind simultaneously to the 26S proteasome and to polyubiquitinated substrates and to deliver ubiquitinated proteins to the proteasome.Involved in nucleotide excision repair and is thought to be functional equivalent for RAD23B in global genome nucleotide excision repair (GG-NER) by association with XPC. In vitro, the XPC:RAD23A dimer has NER activity. Can stabilize XPC.Involved in vpr-dependent replication of HIV-1 in non-proliferating cells and primary macrophages. Required for the association of HIV-1 vpr with the host proteasome.
    Poids moléculaire
    41.6 kDa
    UniProt
    P54725
    Pathways
    Réparation de l'ADN
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