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SPA17 Protein (AA 1-151) (His tag)

SPA17 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS
N° du produit ABIN5852921
  • Antigène Voir toutes SPA17 Protéines
    SPA17 (Sperm Autoantigenic Protein 17 (SPA17))
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 1-151
    Origine
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Source
    • 5
    • 5
    • 2
    • 1
    Escherichia coli (E. coli)
    Purification/Conjugué
    Cette SPA17 protéine est marqué à la His tag.
    Application
    SDS-PAGE (SDS)
    Séquence
    MGSSHHHHHH SSGLVPRGSH MGSMSIPFSN THYRIPQGFG NLLEGLTREI LREQPDNIPA FAAAYFESLL EKREKTNFDP AEWGSKVEDR FYNNHAFEEQ EPPEKSDPKQ EESQISGKEE ETSVTILDSS EEDKEKEEVA AVKIQAAFRG HIAREEAKKM KTNSLQNEEK EENK
    Pureté
    > 90 % by SDS - PAGE
    Top Product
    Discover our top product SPA17 Protéine
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 0.15M NaCl, 10 % glycerol, 1  mM DTT
    Stock
    4 °C,-20 °C,-80 °C
    Stockage commentaire
    Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
  • Antigène
    SPA17 (Sperm Autoantigenic Protein 17 (SPA17))
    Autre désignation
    SPA17 (SPA17 Produits)
    Synonymes
    spa17 Protein, MGC89454 Protein, SPA17 Protein, CT22 Protein, SP17 Protein, SP17-1 Protein, Sp17 Protein, sperm autoantigenic protein 17 Protein, sperm autoantigenic protein 17 L homeolog Protein, spa17 Protein, SPA17 Protein, spa17.L Protein, Spa17 Protein
    Sujet
    SPA17 is a protein present at the cell surface. The N-terminus has sequence similarity to human cAMP-dependent protein kinase A (PKA) type II alpha regulatory subunit (RIIa) while the C-terminus has an IQ calmodulin-binding motif. The central portion of the protein has carbohydrate binding motifs and likely functions in cell-cell adhesion. The protein was initially characterized by its involvement in the binding of sperm to the zona pellucida of the oocyte. Recent studies indicate that it is also involved in additional cell-cell adhesion functions such as immune cell migration and metastasis. Recombinant human SPA17 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
    Poids moléculaire
    19.8 kDa (174aa) confirmed by MALDI-TOF (Molecular size on SDS-PAGE will appear higher)
    NCBI Accession
    NP_059121
    UniProt
    Q15506
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