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PLSCR3 Protein (AA 1-265) (His tag)

PLSCR3 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS
N° du produit ABIN5853314
  • Antigène Voir toutes PLSCR3 Protéines
    PLSCR3 (phospholipid Scramblase 3 (PLSCR3))
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 1-265
    Origine
    • 5
    • 3
    Humain
    Source
    • 2
    • 2
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification/Conjugué
    Cette PLSCR3 protéine est marqué à la His tag.
    Application
    SDS-PAGE (SDS)
    Séquence
    MGSSHHHHHH SSGLVPRGSH MGSMAGYLPP KGYAPSPPPP YPVTPGYPEP ALHPGPGQAP VPAQVPAPAP GFALFPSPGP VALGSAAPFL PLPGVPSGLE FLVQIDQILI HQKAERVETF LGWETCNRYE LRSGAGQPLG QAAEESNCCA RLCCGARRPL RVRLADPGDR EVLRLLRPLH CGCSCCPCGL QEMEVQAPPG TTIGHVLQTW HPFLPKFSIQ DADRQTVLRV VGPCWTCGCG TDTNFEVKTR DESRSVGRIS KQWGGLVREA LTDADDFGLQ FPLDLDVR
    Pureté
    > 90 % by SDS - PAGE
    Top Product
    Discover our top product PLSCR3 Protéine
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Commentaires

    Denatured

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Liquid. 20  mM Tris-HCl buffer (  pH 8.0) containing 10 % glycerol 0.4M urea
    Stock
    4 °C,-20 °C,-80 °C
    Stockage commentaire
    Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
  • Antigène
    PLSCR3 (phospholipid Scramblase 3 (PLSCR3))
    Autre désignation
    PLSCR3 (PLSCR3 Produits)
    Synonymes
    2210403O21Rik Protein, 2610037N06Rik Protein, ESTM3 Protein, X83310 Protein, Pls3 Protein, zgc:77051 Protein, phospholipid scramblase 3 Protein, phospholipid scramblase 3b Protein, PLSCR3 Protein, Plscr3 Protein, plscr3b Protein
    Sujet
    PLSCR3 may mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. This protein may play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system. It seems to play a role in apoptosis, through translocation of cardiolipin from the inner to the outer mitochondrial membrane which promotes BID recruitment and enhances tBid-induced mitochondrial damages. Recombinant human PLSCR3 protein, fused to His-tag at N-terminus, was expressed in E.coli.
    Poids moléculaire
    30.9 kDa (288aa)
    NCBI Accession
    NP_001188505
    UniProt
    Q9NRY6
    Pathways
    Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis
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