PLSCR3 Protein (AA 1-265) (His tag)
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- Antigène Voir toutes PLSCR3 Protéines
- PLSCR3 (phospholipid Scramblase 3 (PLSCR3))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 1-265
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Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette PLSCR3 protéine est marqué à la His tag.
- Application
- SDS-PAGE (SDS)
- Séquence
- MGSSHHHHHH SSGLVPRGSH MGSMAGYLPP KGYAPSPPPP YPVTPGYPEP ALHPGPGQAP VPAQVPAPAP GFALFPSPGP VALGSAAPFL PLPGVPSGLE FLVQIDQILI HQKAERVETF LGWETCNRYE LRSGAGQPLG QAAEESNCCA RLCCGARRPL RVRLADPGDR EVLRLLRPLH CGCSCCPCGL QEMEVQAPPG TTIGHVLQTW HPFLPKFSIQ DADRQTVLRV VGPCWTCGCG TDTNFEVKTR DESRSVGRIS KQWGGLVREA LTDADDFGLQ FPLDLDVR
- Pureté
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product PLSCR3 Protéine
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Commentaires
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Denatured
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Liquid. 20 mM Tris-HCl buffer ( pH 8.0) containing 10 % glycerol 0.4M urea
- Stock
- 4 °C,-20 °C,-80 °C
- Stockage commentaire
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Antigène
- PLSCR3 (phospholipid Scramblase 3 (PLSCR3))
- Autre désignation
- PLSCR3 (PLSCR3 Produits)
- Synonymes
- 2210403O21Rik Protein, 2610037N06Rik Protein, ESTM3 Protein, X83310 Protein, Pls3 Protein, zgc:77051 Protein, phospholipid scramblase 3 Protein, phospholipid scramblase 3b Protein, PLSCR3 Protein, Plscr3 Protein, plscr3b Protein
- Sujet
- PLSCR3 may mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. This protein may play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system. It seems to play a role in apoptosis, through translocation of cardiolipin from the inner to the outer mitochondrial membrane which promotes BID recruitment and enhances tBid-induced mitochondrial damages. Recombinant human PLSCR3 protein, fused to His-tag at N-terminus, was expressed in E.coli.
- Poids moléculaire
- 30.9 kDa (288aa)
- NCBI Accession
- NP_001188505
- UniProt
- Q9NRY6
- Pathways
- Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis
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