BCAR1 Protein (AA 465-848) (His tag)

N° du produit ABIN5853517

Détail du produit

Antigène: BCAR1 (Breast Cancer Anti-Estrogen Resistance 1 (BCAR1))

Type de proteíne: Recombinant

Attributs du protein: AA 465-848

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette BCAR1 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Séquence: MGSSHHHHHH SSGLVPRGSH MGSRLQQGVS ATVAHLLDLA GSAGATGSWR SPSEPQEPLV QDLQAAVAAV QSAVHELLEF ARSAVGNAAH TSDRALHAKL SRQLQKMEDV HQTLVAHGQA LDAGRGGSGA TLEDLDRLVA CSRAVPEDAK QLASFLHGNA SLLFRRTKAT APGPEGGGTL HPNPTDKTSS IQSRPLPSPP KFTSQDSPDG QYENSEGGWM EDYDYVHLQG KEEFEKTQKE LLEKGSITRQ GKSQLELQQL KQFERLEQEV SRPIDHDLAN WTPAQPLAPG RTGGLGPSDR QLLLFYLEQC EANLTTLTNA VDAFFTAVAT NQPPKIFVAH SKFVILSAHK LVFIGDTLSR QAKAADVRSQ VTHYSNLLCD LLRGIVATTK AAALQYPSPS AAQDMVE

Pureté: > 85 % by SDS - PAGE

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

Denatured

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 0.4M uREA, 10 % glycerol

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: BCAR1 (Breast Cancer Anti-Estrogen Resistance 1 (BCAR1))

Autre désignation: BCAR1 (BCAR1 Produits)

Synonymes: CAS Protein, CAS1 Protein, CASS1 Protein, CRKAS Protein, P130Cas Protein, AI385681 Protein, Cas Protein, Crkas Protein, P130CAS Protein, MGC68466 Protein, cas Protein, p130cas Protein, BCAR1 Protein, fc17f11 Protein, wu:fc17f11 Protein, zgc:175192 Protein, BCAR1, Cas family scaffolding protein Protein, breast cancer anti-estrogen resistance 1 Protein, breast cancer anti-estrogen resistance 1 L homeolog Protein, breast cancer anti-estrogen resistance protein 1 Protein, BCAR1 Protein, Bcar1 Protein, bcar1.L Protein, bcar1 Protein, LOC100435586 Protein

Sujet: BCAR1, or CAS, is an Src family kinase substrate involved in various cellular events, including migration, survival, transformation, and invasion. Recombinant human BCAR1 protein, fused to His-tag at N-terminus, was expressed in E.coli.

Poids moléculaire: 43.9kDa (407aa)

NCBI Accession: NP_055382

UniProt: P56945

Pathways: EGFR Signaling Pathway, Neurotrophin Signaling Pathway, CXCR4-mediated Signaling Events, Platelet-derived growth Factor Receptor Signaling