ZNHIT1 Protein (AA 1-154) (His tag)

N° du produit ABIN5853634

Détail du produit

Antigène: ZNHIT1 (Zinc Finger, HIT-Type Containing 1 (ZNHIT1))

Type de proteíne: Recombinant

Attributs du protein: AA 1-154

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette ZNHIT1 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Séquence: MGSSHHHHHH SSGLVPRGSH MGSMVEKKTS VRSQDPGQRR VLDRAARQRR INRQLEALEN DNFQDDPHAG LPQLGKRLPQ FDDDADTGKK KKKTRGDHFK LRFRKNFQAL LEEQNLSVAE GPNYLTACAG PPSRPQRPFC AVCGFPSPYT CVSCGARYCT VRCLGTHQET RCLKWTV

Pureté: > 95 % by SDS - PAGE

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

Denatured

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 10 % glycerol, 0.4M urea

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: ZNHIT1 (Zinc Finger, HIT-Type Containing 1 (ZNHIT1))

Autre désignation: ZNHIT1 (ZNHIT1 Produits)

Synonymes: CG1I Protein, ZNFN4A1 Protein, 2700001K05Rik Protein, zgc:112524 Protein, cg1i Protein, znfn4a1 Protein, zinc finger HIT-type containing 1 Protein, zinc finger, HIT domain containing 1 Protein, zinc finger, HIT-type containing 1 Protein, ZNHIT1 Protein, Znhit1 Protein, znhit1 Protein

Sujet: ZNHIT1 belongs to the ZNHIT1 family and contains 1 HIT-type zinc finger. The protein is induced by DNA damage and seems to play role in p53-mediated apoptosis induction. ZNHIT1 interacts with MAPK11 and MAPK14 and is component of the chromatin-remodeling SRCAP complex composed of at least SRCAP, DMAP1, RuVBL1, RuVBL2, ACTL6A, YEATS4, ACTR6 and ZNHIT1. Recombinant human ZNHIT1 protein, fused to His-tag at N-terminus, was expressed in E.coli .

Poids moléculaire: 19.9 kDa (177aa)

NCBI Accession: NP_006340

UniProt: O43257