GTF2H5 Protein (AA 1-71) (His tag)

N° du produit ABIN5853969

Détail du produit

Antigène: GTF2H5 (General Transcription Factor IIH, Polypeptide 5 (GTF2H5))

Type de proteíne: Recombinant

Attributs du protein: AA 1-71

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette GTF2H5 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Séquence: MGSSHHHHHH SSGLVPRGSH MGSMVNVLKG VLIECDPAMK QFLLYLDESN ALGKKFIIQD IDDTHVFVIA ELVNVLQERV GELMDQNAFS LTQK

Pureté: > 95 % by SDS - PAGE

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Liquid, In Phosphate buffered saline (  pH 7.4) containing 10 % glycerol

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: GTF2H5 (General Transcription Factor IIH, Polypeptide 5 (GTF2H5))

Autre désignation: GTF2H5 (GTF2H5 Produits)

Synonymes: 2700017P07Rik Protein, 2810432H05Rik Protein, D17Wsu155e Protein, C6orf175 Protein, TFB5 Protein, TFIIH Protein, TGF2H5 Protein, TTD Protein, TTD-A Protein, TTDA Protein, bA120J8.2 Protein, RGD1560991 Protein, ttd Protein, tfb5 Protein, ttda Protein, ttd-a Protein, tgf2h5 Protein, ba120j8.2 Protein, si:dkey-12h9.4 Protein, zgc:153434 Protein, general transcription factor IIH, polypeptide 5 Protein, general transcription factor IIH subunit 5 Protein, Gtf2h5 Protein, GTF2H5 Protein, gtf2h5 Protein

Sujet: GTF2H5 is a subunit of transcription/repair factor TFIIH, which functions in gene transcription and DNA repair. This protein stimulates ERCC3/XPB ATPase activity to trigger DNA opening during DNA repair, and is implicated in regulating cellular levels of TFIIH. Mutations in this gene result in trichothiodystrophy, complementation group A. Recombinant human GTF2H5 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Poids moléculaire: 10.4 kDa (94aa) confirmed by MALDI-TOF

NCBI Accession: NP_997001

UniProt: Q6ZYL4

Pathways: Réparation de l'ADN