SFRP5 Protein (AA 30-317) (His tag)

N° du produit ABIN5854078

Détail du produit

Antigène: SFRP5 (Secreted Frizzled-Related Protein 5 (SFRP5))

Type de proteíne: Recombinant

Attributs du protein: AA 30-317

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette SFRP5 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Séquence: MGSSHHHHHH SSGLVPRGSH MGSEEYDYYG WQAEPLHGRS YSKPPQCLDI PADLPLCHTV GYKRMRLPNL LEHESLAEVK QQASSWLPLL AKRCHSDTQV FLCSLFAPVC LDRPIYPCRS LCEAVRAGCA PLMEAYGFPW PEMLHCHKFP LDNDLCIAVQ FGHLPATAPP VTKICAQCEM EHSADGLMEQ MCSSDFVVKM RIKEIKIENG DRKLIGAQKK KKLLKPGPLK RKDTKRLVLH MKNGAGCPCP QLDSLAGSFL VMGRKVDGQL LLMAVYRWDK KNKEMKFAVK FMFSYPCSLY YPFFYGAAEP H

Pureté: > 85 % by SDS - PAGE

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

Denatured

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. In 20  mM Tris-HCl(  pH 8.0) containing 10 % glycerol.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: SFRP5 (Secreted Frizzled-Related Protein 5 (SFRP5))

Autre désignation: SFRP5 (SFRP5 Produits)

Synonymes: SARP3 Protein, AI605071 Protein, D144 Protein, frp1 Protein, zgc:101849 Protein, Sfrp5 Protein, XsFRP5 Protein, frp5 Protein, sFRP-5 Protein, sarp3 Protein, sfrp5 Protein, sfrp5-a Protein, sfrp5-b Protein, secreted frizzled related protein 5 Protein, secreted frizzled-related sequence protein 5 Protein, secreted frizzled-related protein 5 Protein, secreted frizzled-related protein 5 L homeolog Protein, secreted frizzled-related protein 5 S homeolog Protein, SFRP5 Protein, Sfrp5 Protein, sfrp5 Protein, sfrp5.L Protein, sfrp5.S Protein

Sujet: SARP3, also known as secreted frizzled-related protein 5, is a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. SFRP5 and SFRP1 may be involved in determining the polarity of photoreceptor cells in the retina. SFRP5 is highly expressed in the retinal pigment epithelium, and moderately expressed in the pancreas. Recombinant SFRP5, fused to His-tag at N-terminus, was expressed in E.coli.

Poids moléculaire: 35kDa (311aa)

NCBI Accession: NP_003006

UniProt: Q5T4F7

Pathways: Signalisation WNT