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IL13 Receptor alpha 1 Protein (AA 22-343) (His tag)
IL13RA1
Origine: Humain
Hôte: Baculovirus infected Insect Cells
Recombinant
> 90 % by SDS - PAGE.
SDS
N° du produit ABIN5854209
Détail du produit
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Antigène
Voir toutes IL13 Receptor alpha 1 (IL13RA1) Protéines
IL13 Receptor alpha 1 (IL13RA1)
(Interleukin 13 Receptor, alpha 1 (IL13RA1))
Type de proteíne
Recombinant
Attributs du protein
AA 22-343
Origine
Toutes les origines à travers IL13 Receptor alpha 1 Protéines
Humain
Source
Toutes les sources à travers IL13 Receptor alpha 1 Protéines
Baculovirus infected Insect Cells
Purification/Conjugué
Cette IL13 Receptor alpha 1 protéine est marqué à la His tag.
Application
SDS-PAGE (SDS)
Séquence
GGGGAAPTET QPPVTNLSVS VENLCTVIWT WNPPEGASSN CSLWYFSHFG DKQDKKIAPE TRRSIEVPLN ERICLQVGSQ CSTNESEKPS ILVEKCISPP EGDPESAVTE LQCIWHNLSY MKCSWLPGRN TSPDTNYTLY YWHRSLEKIH QCENIFREGQ YFGCSFDLTK VKDSSFEQHS VQIMVKDNAG KIKPSFNIVP LTSRVKPDPP HIKNLSFHND DLYVQWENPQ NFISRCLFYE VEVNNSQTET HNVFYVQEAK CENPEFERNV ENTSCFMVPG VLPDTLNTVR IRVKTNKLCY EDDKLWSNWS QEMSIGKKRN STHHHHHH
Pureté
> 90 % by SDS - PAGE.
niveau d'endotoxine
< 1.0 EU per 1 microgram of protein (determined by LAL method)
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Information d'application
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Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Stockage
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Format
Liquid
Concentration
0.5 mg/mL
Buffer
Liquid. In Phosphate buffer saline ( pH 7.4)
Stock
4 °C,-20 °C,-80 °C
Stockage commentaire
Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Détail du antigène
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Antigène
IL13 Receptor alpha 1 (IL13RA1)
(Interleukin 13 Receptor, alpha 1 (IL13RA1))
Autre désignation
IL13RA1 (IL13RA1 Produits )
Synonymes
CD213A2 Protein, CT19 Protein, IL-13R Protein, IL13BP Protein, CD213A1 Protein, IL-13Ra Protein, NR4 Protein, AI882074 Protein, CD213a1 Protein, IL-13r[a] Protein, Il13ra Protein, IL13RA1 Protein, il-13ra1 Protein, si:ch211-150g2.2 Protein, interleukin 13 receptor subunit alpha 2 Protein, interleukin 13 receptor subunit alpha 1 Protein, interleukin 13 receptor, alpha 1 Protein, interleukin 13 receptor, alpha 1-like Protein, IL13RA2 Protein, IL13RA1 Protein, Il13ra1 Protein, il13ra1 Protein, LOC100360218 Protein
Sujet
IL13RA1, also known as Interleukin-13 receptor subunit alpha-1, is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4. It is essential for allergen-induced airway hyperactivity and mucus hypersecretion. Recombinant human IL13RA1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Poids moléculaire
37.7kDa (328aa) 40-57kDa (SDS-PAGE under reducing conditions.)
NCBI Accession
NP_001551
UniProt
P78552
Pathways
Signalistation JAK/STAT , Positive Regulation of Immune Effector Process , Production of Molecular Mediator of Immune Response
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