Ephrin B3 Protein (EFNB3) (AA 28-226) (His tag)

N° du produit ABIN5854779

Détail du produit

Antigène: Ephrin B3 (EFNB3)

Type de proteíne: Recombinant

Attributs du protein: AA 28-226

Origine: Humain

Source: Baculovirus infected Insect Cells

Purification/Conjugué: Cette Ephrin B3 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Séquence: ADPLSLEPVY WNSANKRFQA EGGYVLYPQI GDRLDLLCPR ARPPGPHSSP NYEFYKLYLV GGAQGRRCEA PPAPNLLLTC DRPDLDLRFT IKFQEYSPNL WGHEFRSHHD YYIIATSDGT REGLESLQGG VCLTRGMKVL LRVGQSPRGG AVPRKPVSEM PMERDRGAAH SLEPGKENLP GDPTSNATSR GAEGPLPPPS MPHHHHHH

Pureté: > 95 % by SDS - PAGE

niveau d'endotoxine: < 1.0 EU per 1 microgram of protein (determined by LAL method)

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: Ephrin B3 (EFNB3)

Autre désignation: EFNB3 (EFNB3 Produits)

Synonymes: efnb3-A Protein, EphB3 Protein, EFNB3 Protein, efnb3 Protein, id:ibd5049 Protein, zgc:111938 Protein, EFL-6 Protein, ELF-3 Protein, Elk-L3 Protein, Epl8 Protein, LERK-8 Protein, NLERK-2 Protein, ELK-L3 Protein, RGD1565678 Protein, EFL6 Protein, EPLG8 Protein, LERK8 Protein, ephrin B3 Protein, ephrin-B3 L homeolog Protein, ephrin-B3b Protein, ephrin-B3 Protein, EFNB3 Protein, efnb3.L Protein, efnb3b Protein, efnb3 Protein, Efnb3 Protein

Sujet: EFNB3, also known as ephrin-B3, is a member of the Ephrin-B family of transmembrane ligands that bind and induce the tyrosine autophosphorylation of Eph receptors. EFNB3 is expressed on oligodendrocytes and neurons in the hippocampus and along the midline of the spinal cord. It is up-regulated in glioma and promotes tumor cell invasion and migration. This protein acts as the midline barrier that prevents corticospinal tract projections from recrossing when they enter the spinal gray matter. Recombinant human EFNB3, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Poids moléculaire: 23.0kDa (208aa) 28-40KDa (SDS-PAGE under reducing conditions.)

NCBI Accession: NP_001397

UniProt: Q15768

Pathways: Signalisation RTK