RNASE3 Protein (AA 28-160) (His tag)

N° du produit ABIN5854791

Détail du produit

Antigène: RNASE3 (ECP) (Eosinophil Cationic Protein (ECP))

Type de proteíne: Recombinant

Attributs du protein: AA 28-160

Origine: Humain

Source: Baculovirus infected Insect Cells

Purification/Conjugué: Cette RNASE3 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Séquence: ADPRPPQFTR AQWFAIQHIS LNPPRCTIAM RAINNYRWRC KNQNTFLRTT FANVVNVCGN QSIRCPHNRT LNNCHRSRFR VPLLHCDLIN PGAQNISNCR YADRPGRRFY VVACDNRDPR DSPRYPVVPV HLDTTIHHHH HH

Pureté: > 95 % by SDS-PAGE

niveau d'endotoxine: < 1.0 EU per 1 microgram of protein (determined by LAL method)

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: RNASE3 (ECP) (Eosinophil Cationic Protein (ECP))

Autre désignation: RNASE3 (ECP Produits)

Synonymes: ECP Protein, RNS3 Protein, ribonuclease A family member 3 Protein, RNASE3 Protein

Sujet: RNASE3, also known as Ribonuclease RNase A family 3, located in the eosinophil primary matrix. It released during degranulation of eosinophils. This protein is related to inflammation and asthma because in these cases, there are increased levels of ECP in the body. It is a potent cytotoxic protein capable of killing cells of guinea pig tracheal epithelium, mammalian leukemia, epidermis carcinoma, and breast carcinoma, as well as non-mammalian cells such as parasites, bacteria, and viruses. Recombinant human RNASE3 protein, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Poids moléculaire: 16.6kDa (142aa) 18-28KDa (SDS-PAGE under reducing conditions.)