AATF Protein (AA 6-294, partial) (GST tag)
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- Antigène Voir toutes AATF Protéines
- AATF (Apoptosis Antagonizing Transcription Factor (AATF))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 6-294, partial
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Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette AATF protéine est marqué à la GST tag.
- Application
- Western Blotting (WB), SDS-PAGE (SDS), ELISA
- Séquence
- PLALQLEQLL NPRPSEADPE ADPEEATAAR VIDRFDEGED GEGDFLVVGS IRKLASASLL DTDKRYCGKT TSRKAWNEDH WEQTLPGSSD EEISDEEGSG DEDSEGLGLE EYDEDDLGAA EEQECGDHRE SKKSRSHSAK TPGFSVQSIS DFEKFTKGMD DLGSSEEEED EESGMEEGDD AEDSQGESEE DRAGDRNSED DGVVMTFSSV KVSEEVEKGR AVKNQIALWD QLLEGRIKLQ KALLTTNQLP QPDVFPLFKD KGGPEFSSAL KNSHKALKAL LRSLVGLQE
- Pureté
- 95 %
- Top Product
- Discover our top product AATF Protéine
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Apoptosis Antagonizing Transcription Factor (AATF) (AA 151-250) protein (GST tag)
AATF Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AA, AP
Apoptosis Antagonizing Transcription Factor (AATF) (AA 1-560) protein (GST tag)AATF Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AA, AP
Apoptosis Antagonizing Transcription Factor (AATF) (AA 2-560) protein (His tag)Crystallography grade AATF Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Apoptosis Antagonizing Transcription Factor (AATF) (AA 2-526) protein (His tag)Crystallography grade AATF Origine: Souris Hôte: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Apoptosis Antagonizing Transcription Factor (AATF) protein (DYKDDDDK Tag)AATF Origine: Humain Hôte: Insect cells (Sf9) Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Apoptosis Antagonizing Transcription Factor (AATF) proteinAATF Origine: Rat Hôte: Escherichia coli (E. coli) Recombinant > 95 % WB, SDS, ELISA, IP
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS buffer, 20mM GSH
- Stock
- 4 °C
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- Antigène
- AATF (Apoptosis Antagonizing Transcription Factor (AATF))
- Autre désignation
- Protein AATF (AATF Produits)
- Synonymes
- AATF Protein, ded Protein, che1 Protein, che-1 Protein, cb109 Protein, sb:cb109 Protein, wu:fc13d05 Protein, zgc:162071 Protein, CHE-1 Protein, CHE1 Protein, DED Protein, 4933415H02Rik Protein, 5830465M17Rik Protein, Che-1 Protein, Trb Protein, Ded Protein, apoptosis antagonizing transcription factor Protein, Apoptosis antagonizing transcription factor Protein, apoptosis antagonizing transcription factor S homeolog Protein, AATF Protein, aatf Protein, BFR2 Protein, NAEGRDRAFT_56916 Protein, Aatf Protein, aatf.S Protein
- Sujet
- Background: May function as a general inhibitor of the histone deacetylase HDAC1. Binding to the pocket region of RB1 may displace HDAC1 from RB1/E2F complexes, leading to activation of E2F target genes and cell cycle progression. Conversely, displacement of HDAC1 from SP1 bound to the CDKN1A promoter leads to increased expression of this CDK inhibitor and blocks cell cycle progression. Also antagonizes PAWR mediated induction of aberrant amyloid peptide production in Alzheimer disease (presenile and senile dementia), although the molecular basis for this phenomenon has not been described to date. Synonyms: Apoptosis-antagonizing transcription factor Rb-binding protein Che-1.
- Poids moléculaire
- 59.1 kD
- NCBI Accession
- NM_012138
- UniProt
- Q9NY61
- Pathways
- Neurotrophin Signaling Pathway, SARS-CoV-2 Protein Interactome
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