BTLA Protein (AA 31-157) (Fc Tag)

N° du produit ABIN6253355

Détail du produit

Antigène: BTLA (B and T Lymphocyte Associated (BTLA))

Type de proteíne: Recombinant

Attributs du protein: AA 31-157

Origine: Humain

Source: CHO Cells

Purification/Conjugué: Cette BTLA protéine est marqué à la Fc Tag.

Fonction: CD272 [BTLA] (human):Fc (human) (rec.)

Specificité: The extracellular domain of human CD272 (aa 31-157) is fused to the N-terminus of the Fc region of human IgG1.

Attributs du produit: Protein. The extracellular domain of human CD272 (aa 31-157) is fused to the N-terminus of the Fc region of human IgG1. Source: CHO cells. Endotoxin content: <0.06EU/μg protein (LAL test, Lonza). Lyophilized from 0.2μm-filtered solution in PBS. Purity: >98 % (SDS-PAGE). BTLA is a type I transmembrane glycoprotein of the CD28 family of T cell costimulatory molecules. BTLA functions as a coinhibitor on activated T cells and on B cells and dendritic cells. The extracellular domain (ECD) of this Ig superfamily protein contains one V-type Ig-like domain, which interacts with HVEM.

Pureté: >98 % (SDS-PAGE)

niveau d'endotoxine: <0.06EU/μg protein (LAL test, Lonza).

Biological Activity Comment: Measured in a competitive binding assay.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized from 0.2μm-filtered solution in PBS.

Conseil sur la manipulation: Avoid freeze/thaw cycles.

Stock: 4 °C,-20 °C

Stockage commentaire:

Short Term Storage: +4°C

Long Term Storage: -20°C

Use & Stability: Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.

Détail du antigène

Antigène: BTLA (B and T Lymphocyte Associated (BTLA))

Autre désignation: CD272 [BTLA] (BTLA Produits)

Synonymes: BTLA Protein, BTLA1 Protein, CD272 Protein, A630002H24 Protein, B and T lymphocyte associated Protein, BTLA Protein, Btla Protein

Sujet:

Alternate Names/Synonyms: BTLA, B- and T-lymphocyte attenuator

Product Description: BTLA is a type I transmembrane glycoprotein of the CD28 family of T cell costimulatory molecules. BTLA functions as a coinhibitor on activated T cells and on B cells and dendritic cells. The extracellular domain (ECD) of this Ig superfamily protein contains one V-type Ig-like domain, which interacts with HVEM.

NCBI Accession: NP_861445

Pathways: Cancer Immune Checkpoints