JAM3 Protein (His tag)

N° du produit ABIN6387034

Détail du produit

Antigène: JAM3 (Junctional Adhesion Molecule 3 (JAM3))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette JAM3 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Purification: purified by chromatography

Pureté: > 90 % by SDS - PAGE

Information d'application

Commentaires:

Synonyms: Junctional adhesion molecule C, Junctional adhesion molecule 3, JAM-C, JAMC

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/ml (determined by Bradford assay)

Buffer: 20 mM Tris-HCl buffer (pH 8.0) containing 0.2 M NaCl, 50% glycerol, 2 mM EDTA, 5 MM DTT

Stock: 4 °C

Stockage commentaire: Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: JAM3 (Junctional Adhesion Molecule 3 (JAM3))

Autre désignation: JAM3 (JAM3 Produits)

Synonymes: JAM3 Protein, jam3 Protein, sr:nyz155 Protein, wu:fb30h11 Protein, wu:fc08c06 Protein, wu:fc13e04 Protein, wu:fc25g11 Protein, jamc.2 Protein, 1110002N23Rik Protein, JAM-3 Protein, JAM-C Protein, Jcam3 Protein, JAM-2 Protein, JAMC Protein, junctional adhesion molecule 3 Protein, junctional adhesion molecule 3b Protein, junctional adhesion molecule 3a Protein, junction adhesion molecule 3 Protein, JAM3 Protein, jam3b Protein, jam3a Protein, Jam3 Protein

Sujet: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. JAM3 is localized in the tight junctions between high endothelial cells. Unlike other proteins in this family, this protein is unable to adhere to leukocyte cell lines and only forms weak homotypic interactions. JAM3 is a member of the junctional adhesion molecule protein family and acts as a receptor for another member of this family. Recombinant human JAM3 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Poids moléculaire: 26 kDa (234aa), confirmed by MALDI-TOF

NCBI Accession: NP_116190