Beclin 1 Protein (His tag)
-
- Antigène Voir toutes Beclin 1 (BECN1) Protéines
- Beclin 1 (BECN1) (Beclin 1, Autophagy Related (BECN1))
- Type de proteíne
- Recombinant
-
Origine
- Humain
-
Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette Beclin 1 protéine est marqué à la His tag.
- Application
- SDS-PAGE (SDS)
- Purification
- purified by chromatography
- Pureté
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product BECN1 Protéine
-
-
- Commentaires
-
Synonyms: beclin 1, ATG6, beclin1, VPS30
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 0.25 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.5) containing 0.1 M NaCl, 10% glycerol,1 MM DTT
- Stock
- 4 °C
- Stockage commentaire
- Avoid repeated freezing and thawing cycles.
-
- Antigène
- Beclin 1 (BECN1) (Beclin 1, Autophagy Related (BECN1))
- Autre désignation
- BECN1 (BECN1 Produits)
- Synonymes
- beclin-1 Protein, atg6 Protein, vps30 Protein, beclin1 Protein, Beclin-1 Protein, becn1 Protein, zgc:73097 Protein, ATG6 Protein, VPS30 Protein, 4921513J16Rik Protein, 5430417M23Rik Protein, Atg6 Protein, beclin 1 Protein, beclin 1, autophagy related Protein, beclin 1 protein Protein, beclin-1 Protein, beclin family protein Protein, beclin 1, autophagy related L homeolog Protein, BECN1 Protein, becn1 Protein, atg6 Protein, CpipJ_CPIJ011087 Protein, PTRG_07825 Protein, SJAG_01876 Protein, Becn1 Protein, becn1.L Protein
- Sujet
- BECN1, also as known as Beclin-1 and autophagy-related gene (Atg) 6, belongs to the beclin family. This protein plays a central role in autophagy. Beclin-1 and its binding partner class III phosphoinositide 3-kinase (PI3K), also named Vps34, are required for the initiation of the formation of the autophagasome in autophagy. Also it required for the abcission step of cytokinesis. BECN1 plays a role in antiviral host defense. Recombinant human BECN1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by conventional column chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.
- Poids moléculaire
- 54.1 kDa (470aa)
- NCBI Accession
- NP_003757
- Pathways
- Autophagy
-