GALT Protein (His tag)

N° du produit ABIN6387110

Détail du produit

Antigène: GALT (Galactose-1-Phosphate Uridylyltransferase (GALT))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette GALT protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Purification: purified by chromatography

Pureté: > 85 % by SDS - PAGE

Information d'application

Commentaires:

Synonyms: Galactose-1-phosphate uridylyltransferase, Gal-1-P uridylyltransferase, UDP-glucose--hexose-1-phosphate uridylyltransferase

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/ml (determined by Bradford assay)

Buffer: 20 mM Tris-HCl buffer (pH 8.5) containing 0.2 M NaCl, 10% glycerol.

Stock: 4 °C

Stockage commentaire: Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: GALT (Galactose-1-Phosphate Uridylyltransferase (GALT))

Autre désignation: GALT (GALT Produits)

Synonymes: GALT Protein, AW553376 Protein, CG9232 Protein, Dmel\\CG9232 Protein, dGALT Protein, galactose-1-phosphate uridylyltransferase Protein, galactose-1-phosphate uridylyltransferase, GalT Protein, probable galactose-1-phosphate uridylyltransferase galtb [second part] Protein, UDP-glucose--galactose-1-phosphate uridylyltransferase Protein, GalT galactose-1-phosphate uridylyltransferase Protein, galactose-1-phosphate uridyl transferase Protein, Galactose-1-phosphate uridylyltransferase Protein, galactose-1-phosphate uridylyltransferase S homeolog Protein, GALT Protein, galT Protein, Galt Protein, CNM00620 Protein, Mrub_2813 Protein, Mesil_2395 Protein, Trad_0989 Protein, Igag_1846 Protein, VDIS_RS10425 Protein, Intca_2810 Protein, Marky_2157 Protein, Selsp_1876 Protein, Trebr_2368 Protein, Halhy_5538 Protein, Theth_1357 Protein, galt.S Protein

Sujet: GALT catalyzes the second step of the Leloir pathway of galactose metabolism, namely the conversion of UDP-glucose + galactose-1-phosphate to glucose-1-phosphate + UDP-galactose. The absence of this enzyme results in classic galactosemia in humans and can be fatal in the newborn period if lactose is not removed from the diet. The pathophysiology of galactosemia has not been clearly defined. Two transcript variants encoding different isoforms have been found for this gene. Recombinant human GALT protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques

Poids moléculaire: 45.9 kDa (403aa), confirmed by MALDI-TOF

NCBI Accession: NP_000146