MAGED1 Protein (AA 504-760) (His tag)

N° du produit ABIN6387343

Détail du produit

Antigène: MAGED1 (Melanoma Antigen Family D, 1 (MAGED1))

Type de proteíne: Recombinant

Attributs du protein: AA 504-760

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette MAGED1 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Séquence: MGSSHHHHHH SSGLVPRGSH MGSLRPSPNS RASQNPGAAQ PRDVALLQER ANKLVKYLML KDYTKVPIKR SEMLRDIIRE YTDVYPEIIE RACFVLEKKF GIQLKEIDKE EHLYILISTP ESLAGILGTT KDTPKLGLLL VILGVIFMNG NRASEAVLWE ALRKMGLRPG VRHPLLGDLR KLLTYEFVKQ KYLDYRRVPN SNPPEYEFLW GLRSYHETSK MKVLRFIAEV QKRDPRDWTA QFMEAADEAL DALDAAAAEA EARAEARTRM GIGDEAVSGP

Pureté: > 85 % by SDS - PAGE

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: Liquid. 20  mM Tris-HCl buffer (  pH 8.0) containing 20 % glycerol, 1  mM DTT

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: MAGED1 (Melanoma Antigen Family D, 1 (MAGED1))

Autre désignation: MAGED1 (MAGED1 Produits)

Synonymes: MAGED1 Protein, DLXIN-1 Protein, NRAGE Protein, 2810433C11Rik Protein, 5430405L04Rik Protein, DXBwg1492e Protein, Dlixin Protein, Dlxin-1 Protein, Dlxin1 Protein, MAGE-D1 Protein, mFLJ00163 Protein, Nrage Protein, MAGE family member D1 Protein, melanoma antigen family D, 1 Protein, melanoma antigen, family D, 1 Protein, MAGED1 Protein, Maged1 Protein

Sujet: MAGED1, as known as Melanoma-associated antigen D1, is expressed in almost all normal adult tissues. It has been demonstrated to be involved in the p75 neurotrophin receptor mediated programmed cell death pathway. It has been involved in Prader-Willi syndrome, which includes hyperphagia, repetitive and compulsive behaviors, and cognitive impairment. Recombinant human MAGED1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.

Poids moléculaire: 31.7kDa (280aa), confirmed by MALDI-TOF

NCBI Accession: NP_001005333

UniProt: Q9Y5V3

Pathways: Neurotrophin Signaling Pathway