CRTAP Protein (AA 27-401) (His tag)

N° du produit ABIN6387378

Détail du produit

Antigène: CRTAP (Cartilage Associated Protein (CRTAP))

Type de proteíne: Recombinant

Attributs du protein: AA 27-401

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette CRTAP protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Séquence: MGSSHHHHHH SSGLVPRGSH MGSQYERYSF RSFPRDELMP LESAYRHALD KYSGEHWAES VGYLEISLRL HRLLRDSEAF CHRNCSAAPQ PEPAAGLASY PELRLFGGLL RRAHCLKRCK QGLPAFRQSQ PSREVLADFQ RREPYKFLQF AYFKANNLPK AIAAAHTFLL KHPDDEMMKR NMAYYKSLPG AEDYIKDLET KSYESLFIRA VRAYNGENWR TSITDMELAL PDFFKAFYEC LAACEGSREI KDFKDFYLSI ADHYVEVLEC KIQCEENLTP VIGGYPVEKF VATMYHYLQF AYYKLNDLKN AAPCAVSYLL FDQNDKVMQQ NLVYYQYHRD TWGLSDEHFQ PRPEAVQFFN VTTLQKELYD FAKENIMDDD EGEVVEYVDD LLELEETS

Pureté: > 85 % by SDS - PAGE

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

Denatured

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 0.4M urea, 10 % glycerol

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: CRTAP (Cartilage Associated Protein (CRTAP))

Autre désignation: CRTAP (CRTAP Produits)

Synonymes: zgc:85621 Protein, wu:fb47h01 Protein, CASP Protein, LEPREL3 Protein, OI7 Protein, 5730529N23Rik Protein, Leprel3 Protein, RGD1565180 Protein, cartilage associated protein Protein, cartilage-associated protein Protein, crtap Protein, CRTAP Protein, LOC5574430 Protein, CpipJ_CPIJ013810 Protein, Crtap Protein

Sujet: Cartilage-associated protein precursor, also known as CRTAP, is a secreted protein localizing to the extracellular space that plays a role in collagen post-translational modifications, extracellular fibril assembly and intracellular trafficking. CRTAP is widely expressed with predominant expression in articular chondrocytes. Mutations in the gene encoding CRTAP can lead to autosomal recessive osteogenesis imperfecta (OI) type 7 and type 2B. OI, also known as brittle bone disease, is characterized by bone fragility and susceptibility to fractures. Recombinant human CRTAP protein, fused to His-tag at N-terminus, was expressed in E.coli.

Poids moléculaire: 46.4 kDa (398aa)

NCBI Accession: NP_006362

UniProt: O75718