NAPSA Protein (AA 64-420) (His tag)

N° du produit ABIN6387805

Détail du produit

Antigène: NAPSA (Napsin A Aspartic Peptidase (NAPSA))

Type de proteíne: Recombinant

Attributs du protein: AA 64-420

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette NAPSA protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Séquence: MGSSHHHHHH SSGLVPRGSH MGSKPIFVPL SNYRDVQYFG EIGLGTPPQN FTVAFDTGSS NLWVPSRRCH FFSVPCWLHH RFDPKASSSF QANGTKFAIQ YGTGRVDGIL SEDKLTIGGI KGASVIFGEA LWEPSLVFAF AHFDGILGLG FPILSVEGVR PPMDVLVEQG LLDKPVFSFY LNRDPEEPDG GELVLGGSDP AHYIPPLTFV PVTVPAYWQI HMERVKVGPG LTLCAKGCAA ILDTGTSLIT GPTEEIRALH AAIGGIPLLA GEYIILCSEI PKLPAVSFLL GGVWFNLTAH DYVIQTTRNG VRLCLSGFQA LDVPPPAGPF WILGDVFLGT YVAVFDRGDM KSSARVGLAR ARTRGADLGW GETAQAQFPG

Pureté: > 90 % by SDS - PAGE

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: Liquid. In 20  mM Tris-HCl (  pH 8.0) containing 10 % glycerol

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: NAPSA (Napsin A Aspartic Peptidase (NAPSA))

Autre désignation: NAPSA (NAPSA Produits)

Synonymes: KAP Protein, Kdap Protein, NAP1 Protein, NAPA Protein, SNAPA Protein, pronapsin Protein, kap Protein, kdap Protein, nap1 Protein, napa Protein, napsa Protein, snapa Protein, napsin A aspartic peptidase Protein, napsin A aspartic peptidase L homeolog Protein, NAPSA Protein, Napsa Protein, napsa.L Protein

Sujet: NAPSA, also known as Napsin-A, belongs to the peptidase A1 family and may be involved in processing of pneumocyte surfactant precursors. The activation peptides of aspartic proteinases plays role as inhibitors of the active site. These peptide segments, or pro-parts, are deemed important for correct folding, targeting, and control of the activation of aspartic proteinase zymogens. The pronapsin A is predicted to be a fully functional, glycosylated aspartic proteinase precursor containing an RGD motif and an additional 18 residues at its C-terminus. Recombinant human NAPSA, fused to His-tag at N-terminus, was expressed in E.coli and purified by conventional chromatography.

Poids moléculaire: 40.9 kDa (380 aa) confirmed by MALDI-TOF

NCBI Accession: NP_004842

UniProt: O96009

Pathways: Tube Formation, Asymmetric Protein Localization, Embryonic Body Morphogenesis