DcR2 Protein (AA 56-211) (hIgG-His-tag)
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- Antigène Voir toutes DcR2 (TNFRSF10D) Protéines
- DcR2 (TNFRSF10D) (Tumor Necrosis Factor Receptor Superfamily, Member 10d, Decoy with Truncated Death Domain (TNFRSF10D))
- Type de proteíne
- Recombinant
- Activité biologique
- Active
- Attributs du protein
- AA 56-211
- Origine
- Humain
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Source
- Baculovirus infected Insect Cells
- Purification/Conjugué
- Cette DcR2 protéine est marqué à la hIgG-His-tag.
- Application
- SDS-PAGE (SDS)
- Séquence
- ATIPRQDEVP QQTVAPQQQR RSLKEEECPA GSHRSEYTGA CNPCTEGVDY TIASNNLPSC LLCTVCKSGQ TNKSSCTTTR DTVCQCEKGS FQDKNSPEMC RTCRTGCPRG MVKVSNCTPR SDIKCKNESA ASSTGKTPAA EETVTTILGM LASPYHVEPK SCDKTHTCPP CPAPELLGGP SVFLFPPKPK DTLMISRTPE VTCVVVDVSH EDPEVKFNWY VDGVEVHNAK TKPREEQYNS TYRVVSVLTV LHQDWLNGKE YKCKVSNKAL PAPIEKTISK AKGQPREPQV YTLPPSRDEL TKNQVSLTCL VKGFYPSDIA VEWESNGQPE NNYKTTPPVL DSDGSFFLYS KLTVDKSRWQ QGNVFSCSVM HEALHNHYTQ KSLSLSPGKH HHHHH
- Pureté
- > 90 % by SDS - PAGE
- niveau d'endotoxine
- < 1.0 EU per 1ug of protein (determined by LAL method)
- Biological Activity Comment
- Measured in a neutralizing assay using Jurkat human T lymphocyte. The ED50 for this effect is less or equal to 10 ng/ml in the presence of 2ng/ml TRAIL.
- Top Product
- Discover our top product TNFRSF10D Protéine
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Commentaires
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Bioactivity Validated
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol.
- Stock
- 4 °C,-20 °C,-80 °C
- Stockage commentaire
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Antigène
- DcR2 (TNFRSF10D) (Tumor Necrosis Factor Receptor Superfamily, Member 10d, Decoy with Truncated Death Domain (TNFRSF10D))
- Autre désignation
- TNFRSF10D (TNFRSF10D Produits)
- Synonymes
- TNFRSF10D Protein, CD264 Protein, DCR2 Protein, TRAIL-R4 Protein, TRAILR4 Protein, TRUNDD Protein, TNF receptor superfamily member 10d Protein, tumor necrosis factor receptor superfamily member 10D Protein, TNFRSF10D Protein, LOC716901 Protein
- Sujet
- TNFRSF10D, also known as tumor necrosis factor receptor superfamily member 10D, is a member of the TNF-receptor superfamily. This protein contains an extracellular TRAIL-binding domain, a transmembrane domain, and a truncated cytoplasmic death domain. Also, it is can protect cells bearing TRAIL R1 and/or TRAIL R2 from TRAIL-mediated apoptosis. Recombinant human TNFRSF10D, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
- Poids moléculaire
- 43.8kDa (395aa) 40-57kDa (SDS-PAGE under reducing conditions)
- NCBI Accession
- NP_003831
- UniProt
- Q9UBN6
- Pathways
- Apoptose
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