PKM2 Protein (AA 1-531) (His tag)

N° du produit ABIN666913

Détail du produit

Antigène: PKM2 (Pyruvate Kinase M2 (PKM2))

Type de proteíne: Recombinant

Attributs du protein: AA 1-531

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette PKM2 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Attributs du produit: PKM2, 1-531aa, Human, His tag, E.coli

Pureté: > 95 % by SDS - PAGE

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol

Stock: 4 °C

Détail du antigène

Antigène: PKM2 (Pyruvate Kinase M2 (PKM2))

Autre désignation: PKM2 (PKM2 Produits)

Synonymes: CTHBP Protein, OIP3 Protein, PK3 Protein, PKM2 Protein, TCB Protein, THBP1 Protein, AA414905 Protein, AL024370 Protein, AL024424 Protein, Pk-2 Protein, Pk-3 Protein, Pk3 Protein, Pkm2 Protein, PKM12 Protein, PKM Protein, pyruvate kinase M1/2 Protein, pyruvate kinase, muscle Protein, PKM Protein, Pkm Protein

Sujet: PKM2 is an isoenzyme of the glycolytic enzyme pyruvate kinase. This protein catalyzes the production of pyruvate and ATP from phosphoenolpyruvate. PKM2 interacting with Opa proteins, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, is required for bacterial pathogenesis. It is specifically expressed at high levels in tumor cells, and can be measured in plasma of patients with advanced breast cancer. Recombinant human PKM2, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: CTHBP, THBP1, p58, M2-PK, Tumor M2-PK, PK2, PK3, PKM, pyruvate kinase, muscle isoform M2 OIP3, PKM, TCB, OPA interacting protein 3, PKM2, Cytosolic thyroid hormone binding protein, Pyruvate kinase 2/3, Pyruvate kinase isozymes M1/M2, Pyruvate kinase muscle, Thyroid hormone binding protein cytosolic. NCBI no.: NP_002645

Poids moléculaire: 60.1 kDa (551aa)

Pathways: L'effet Warburg