GOPC Protein (AA 278-454) (His tag)

N° du produit ABIN666947

Détail du produit

Antigène: GOPC (Golgi-Associated PDZ and Coiled-Coil Motif Containing (GOPC))

Type de proteíne: Recombinant

Attributs du protein: AA 278-454

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette GOPC protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Attributs du produit: GOPC, 278-454aa, Human, His tag, E.coli

Pureté: > 90 % by SDS-PAGE

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol, 1mM DTT.

Stock: 4 °C

Détail du antigène

Antigène: GOPC (Golgi-Associated PDZ and Coiled-Coil Motif Containing (GOPC))

Autre désignation: GOPC (GOPC Produits)

Synonymes: DKFZp459H2130 Protein, 2210402P09Rik Protein, AI844555 Protein, CAL Protein, FIG Protein, GOPC1 Protein, PIST Protein, fe38f01 Protein, wu:fe38f01 Protein, zgc:56254 Protein, zgc:65853 Protein, dJ94G16.2 Protein, cal Protein, gopc1 Protein, pist Protein, golgi associated PDZ and coiled-coil motif containing Protein, golgi-associated PDZ and coiled-coil motif containing Protein, golgi-associated PDZ and coiled-coil motif containing S homeolog Protein, GOPC Protein, Gopc Protein, gopc Protein, gopc.S Protein

Sujet: GOPC, also known as PIST, is a PDZ domain-containing Golgi protein. This protein functions as a homooligomer that interacts with a variety of proteins and plays a role in intracellular protein trafficking and degradation. Additionally, GOPC is thought to regulate ionic currents via membrane channel modification and may also play a role in autophagy. Chromosomal aberrations in the gene encoding GOPC are found in glioblastoma multiform (GBM), a common and aggressive form of brain tumor, suggesting a role for mutated PIST in carcinogenesis. Recombinant GOPC protein was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: CAL, dJ94G16.2, FIG, GOPC1, PIST, Golgi-associated PDZ and coiled-coil motif-containing protein CFTR associated ligand, dJ94G16.2, FIG Fused in glioblastoma, Golgi associated PDZ and coiled coil motif containing, Golgi associated PDZ and coiled coil motif containing protein, GOPC 1, OTTHUMP00000040403, PDZ protein interacting specifically with TC 10, PDZ protein interacting specifically with TC10, PDZ/coiled coil domain binding partner for the rho family GTPase TC 10, PDZ/coiled coil domain binding partner for the rho family GTPase TC10, Protein interacting specifically with Tc 10, Protein interacting specifically with Tc10. NCBI no.: NP_001017408

Poids moléculaire: 21.5 kDa (198aa), confirmed by MALDI-TOF. (Molecular weight on SDS-PAGE will appear higher)

Pathways: Maintenance of Protein Location, Asymmetric Protein Localization