Cyclin H Protein (CCNH) (AA 1-323) (His tag)

N° du produit ABIN666973

Détail du produit

Antigène: Cyclin H (CCNH)

Type de proteíne: Recombinant

Attributs du protein: AA 1-323

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette Cyclin H protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Attributs du produit: Cyclin H, 1- 323 aa, Human, His-tagged, Recombinant, E.coli

Pureté: > 90 % by SDS - PAGE

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 2mM DTT, 30% glycerol, 2mM EDTA, 0.1M NaCl

Stock: 4 °C

Détail du antigène

Antigène: Cyclin H (CCNH)

Autre désignation: Cyclin H (CCNH Produits)

Synonymes: zgc:114132 Protein, cak Protein, p34 Protein, p37 Protein, Cych Protein, ACYPI004637 Protein, ccnh Protein, Cyclin-H Protein, 142767_at Protein, CG7405 Protein, Dmel\\CG7405 Protein, CAK Protein, 6330408H09Rik Protein, AI661354 Protein, AV102684 Protein, AW538719 Protein, ccnh-A Protein, cyclin H Protein, cyclin-H Protein, Cyclin H Protein, CYclin H Protein, cyclin H L homeolog Protein, CCNH Protein, ccnh Protein, LOC5577539 Protein, Cych Protein, CycH Protein, cyh-1 Protein, Ccnh Protein, ccnh.L Protein

Sujet: Cyclin H, also known as CDK7, is a member of the cyclin-dependent protein kinase family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. Cyclin H forms a trimeric complex with cyclin H and MAT1, which functions as a CDK-activating kinase (CAK). Cyclin H is an essential component of the transcription factor TFIIH that is involved in transcription initiation and DNA repair. Recombinant human Cyclin H, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: CCNH, CAK, p34, p37, 6330408H09Rik, AI661354, AV102684, AW538719, CDK activating kinase, Cyclin dependent kinase activating kinase, Cyclin H, CyclinH, MO15 associated protein, P36, Cyclin-H. NCBI no.: NP_001230

Poids moléculaire: 39.8 kDa (343aa), confirmed by MALDI-TOF

Pathways: Cycle Cellulaire, Mitotic G1-G1/S Phases, M Phase