NCK1 Protein (AA 1-377) (His tag)

N° du produit ABIN667017

Détail du produit

Antigène: NCK1 (NCK Adaptor Protein 1 (NCK1))

Type de proteíne: Recombinant

Attributs du protein: AA 1-377

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette NCK1 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Attributs du produit: NCK1, 1-377aa, Human, His tag, E.coli

Pureté: > 90 % by SDS - PAGE

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 20% glycerol, 1mM EDTA, 50mM NaCl

Stock: 4 °C

Détail du antigène

Antigène: NCK1 (NCK Adaptor Protein 1 (NCK1))

Autre désignation: NCK1 (NCK1 Produits)

Synonymes: NCK Protein, NCKalpha Protein, nck-1 Protein, NCK1 Protein, 6330586M15Rik Protein, D230010O13Rik Protein, Nck Protein, Nck-1 Protein, Nck1 Protein, nck Protein, nck1-a Protein, nck1-b Protein, nckalpha Protein, NCK adaptor protein 1 Protein, non-catalytic region of tyrosine kinase adaptor protein 1 Protein, NCK adaptor protein 1b Protein, NCK adaptor protein 1 L homeolog Protein, NCK1 Protein, Nck1 Protein, nck1b Protein, nck1.L Protein

Sujet: NCK adaptor protein 1, also known as NCK, belongs to the adaptor family of proteins. The protein encoded by this gene is one of the signaling and transforming proteins containing Src homology 2 and 3 (SH2 and SH3) domains. It is located in the cytoplasm and is an adaptor protein involved in transducing signals from receptor tyrosine kinases to downstream signal recipients such as RAS. Overexpression of Nck resulted in transformation of NIH 3T3 and 3Y1 rat fibroblast. Recombinant human NCK1, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: NCK, NCKalpha, NCK adaptor protein 1 GRB4, melanoma NCK protein, MGC12668, NCK adaptor protein 2, NCK tyrosine kinase, NCKbeta, non catalytic region of tyrosine kinase, noncatalytic region of tyrosine kinase, beta, SH2/SH3 adaptor protein NCK alpha, SH2/SH3 adaptor protein NCK beta. NCBI no.: NP_006144

Poids moléculaire: 45 kDa (397aa), confirmed by MALDI-TOF

Pathways: TCR Signaling, Regulation of Actin Filament Polymerization, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals