Transgelin Protein (TAGLN) (AA 1-201) (His tag)

N° du produit ABIN667026

Détail du produit

Antigène: Transgelin (TAGLN)

Type de proteíne: Recombinant

Attributs du protein: AA 1-201

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette Transgelin protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Attributs du produit: TAGLN, 1-201aa, Human, His tag, E.coli

Pureté: > 85 % by SDS-PAGE

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 20% glycerol 1mM DTT

Stock: 4 °C

Détail du antigène

Antigène: Transgelin (TAGLN)

Autre désignation: TAGLN (TAGLN Produits)

Synonymes: MGC68550 Protein, sm22 Protein, smcc Protein, tagln1 Protein, ws3-10 Protein, MGC107855 Protein, SM22 Protein, SMCC Protein, TAGLN1 Protein, WS3-10 Protein, Sm22 Protein, Sm22a Protein, Ws310 Protein, SM22A Protein, zgc:153186 Protein, transgelin L homeolog Protein, transgelin Protein, tagln.L Protein, tagln Protein, LOC732906 Protein, TAGLN Protein, tagl Protein, LOC100009332 Protein, Tagln Protein

Sujet: TAGLN is a transformation and shape-change sensitive actin cross-linking/gelling protein that belongs to the calponin family. This protein is expressed abundantly in fibroblasts and smooth muscle. It is involved in calcium interactions and contractile properties of the cell that may contribute to replicative senescence. During embryogenesis, TAGLN is expressed in smooth, cardiac and skeletal muscle, but is restricted during late fetal development and adulthood to all vascular and visceral smooth muscle cells and low levels of expression in heart. It is downregulated in several transformed cell lines, indicating that a reduction of TAGLN expression may be an early indicator of the onset of transformation. Recombinant human TAGLN protein, fused to his-tag at N-terminus was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: SM22, SMCC, TAGLN1, WS3-10, Transgelin, SM 22, SM22 alpha, SMCC, Smooth muscle protein 22-alpha, WS3 10. NCBI no.: NP_001001522

Poids moléculaire: 24.8 kDa (221aa) confirmed by MALDI-TOF