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TANK Protein (AA 1-119)

TANK Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS
N° du produit ABIN667036
  • Antigène Voir toutes TANK Protéines
    TANK (TRAF Family Member-Associated NFKB Activator (TANK))
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 1-119
    Origine
    • 7
    • 1
    Humain
    Source
    • 3
    • 2
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Application
    SDS-PAGE (SDS)
    Attributs du produit
    TANK, 1-119 aa, Human, Recombinant, E.coli
    Pureté
    > 90 % by SDS - PAGE
    Top Product
    Discover our top product TANK Protéine
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/ml (determined by Bradford assay)
    Buffer
    Liquid. In 20mM Tris-HCl buffer (pH8.0)
    Stock
    4 °C
  • Antigène
    TANK (TRAF Family Member-Associated NFKB Activator (TANK))
    Autre désignation
    TANK (TANK Produits)
    Synonymes
    I-TRAF Protein, ITRAF Protein, TRAF2 Protein, C86182 Protein, E430026L09Rik Protein, zgc:153048 Protein, i-traf Protein, tank Protein, traf2 Protein, TRAF family member associated NFKB activator Protein, TRAF family member-associated Nf-kappa B activator Protein, TRAF family member-associated NFKB activator Protein, TRAF family member associated NFKB activator L homeolog Protein, TANK Protein, Tank Protein, tank Protein, tank.L Protein
    Sujet
    TANK, also known as TRAF(tumor necrosis factor receptor-associated Factor)-interacting protein, is found in the cytoplasm and can bind to TRAF1, TRAF2, or TRAF3, thereby proposing that this protein is an inhibitor of TRAF function that regulates TRAF protein activity by sequestering TRAFs in a latent state in the cytoplasm. Overexpression of TANK inhibits TRAF2-mediated NF-Kappa-B activation signaled by CD40 and both TNF receptors and inhibits LMP1-mediated NF-kappa-B activation by blocking the association of TRAF2 with LMP1. Recombinant human TANK protein was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: TRAF interacting protein TANK isoform b, I-TRAF, TRAF2, TRAF interacting protein TANK isoform b I TRAF, ITRAF, TRAF interacting protein, TRAF family member associated NF KAPPA B activator, TRAF family member associated NFKB activator, TRAF interacting protein TANK isoform a. NCBI no.: NP_597841
    Poids moléculaire
    13.6 kDa (119 aa), confirmed by MALDI-TOF.
    Pathways
    Signalisation p53, Signalisation TLR, Activation of Innate immune Response
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