CRADD Protein (AA 1-199) (His tag)

N° du produit ABIN667087

Détail du produit

Antigène: CRADD (CASP2 and RIPK1 Domain Containing Adaptor with Death Domain (CRADD))

Type de proteíne: Recombinant

Attributs du protein: AA 1-199

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette CRADD protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Attributs du produit: CRADD, 1-199aa, Human,His tagged, Recombinant, E.coli

Pureté: > 95 % by SDS - PAGE

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid in 20mM TRIS pH 8.0, 20% glycerol

Stock: 4 °C

Détail du antigène

Antigène: CRADD (CASP2 and RIPK1 Domain Containing Adaptor with Death Domain (CRADD))

Autre désignation: CRADD (CRADD Produits)

Synonymes: cradd Protein, MGC89035 Protein, zgc:101717 Protein, CRADD Protein, DKFZp468A2219 Protein, LOC100226369 Protein, raidd Protein, MGC78788 Protein, MRT34 Protein, RAIDD Protein, CASP2 and RIPK1 domain containing adaptor with death domain Protein, CASP2 and RIPK1 domain containing adaptor with death, gene 1 Protein, CASP2 and RIPK1 domain containing adaptor with death, gene 2 S homeolog Protein, CRADD Protein, cradd.1 Protein, cradd Protein, cradd.2.S Protein, Cradd Protein

Sujet: CRADD is a 22 kDa, widely-expressed cytosolic adaptor protein. CRADD is a death domain (CARD/DD) containing protein and has been shown to induce cell apoptosis. Through its CARD domain, this protein interacts with, and thus recruits, caspase 2/ICH1 to the cell death signal transduction complex that includes tumor necrosis factor receptor 1 (TNFR1A), RIPK1/RIP kinase, and numbers of other CARD domain-containing proteins. Recombinant CRADD protein was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: RAIDD, CRADD, Caspase and RIP adapter with death domain, Caspase and RIP adapter with death domain CASP2 and RIPK1 domain containing adaptor with death domain, Death adaptor molecule RAIDD, Death domain containing protein CRADD, MGC9163, RIP associated ICH1/CED3 homologous protein with death domain, RIP associated protein with a death domain,. NCBI no.: NP_003796

Poids moléculaire: 24.9kDa (219aa), confirmed by MALDI-TOF.

Pathways: Apoptose, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity