AKR1B11 Protein, AKR1B12 Protein, ALDRLn Protein, ARL-1 Protein, ARL1 Protein, HIS Protein, HSI Protein, 2310005E10Rik Protein, Akr1b16 Protein, AKR Protein, AKR1B10 Protein, Akr1b10 Protein, aldo-keto reductase family 1 member B10 Protein, aldo-keto reductase family 1, member B10 (aldose reductase) Protein, aldo-keto reductase family 1 member B10-like 2 Protein, AKR1B10 Protein, Akr1b10 Protein, AKR1B10L2 Protein, LOC100585902 Protein, LOC100723118 Protein, LOC101107697 Protein
Sujet
AKR1B10, also known as Aldo-keto reductase family 1, member B10, AKR1B10 is a monomeric protein that efficiently catalyzes the reduction of aromatic and aliphatic aldehydes and ketones. AKR1B10 is ubiquitously expressed in many human tissues but is highly expressed in small intestine, colon and adrenal gland. This protein is pathogenically involved in diabetic complications and has been reported that AKR1B10 is overexpressed in human tumors, such as liver, breast, and lung cancer, and may play a critical role in the development and progression of cancer. Recombinant human AKR1B10 protein was expressed in E.coli and purified by using conventional chromatography. Synonyms: AKR1B11, AKR1B12, ALDRLn, ARL-1, ARL1, HIS, HIS, Aldo-keto reductase family 1, member B10, AKR1B10, Aldo-keto reductase family 1, member B10 Aldose reductase like, Aldose reductase related protein, ARL 1, hARP, SI reductase, Small intestine reductase. NCBI no.: NP_064695