PMM2 Protein (AA 1-246) (His tag)

N° du produit ABIN667222

Détail du produit

Antigène: PMM2 (Phosphomannomutase 2 (PMM2))

Type de proteíne: Recombinant

Attributs du protein: AA 1-246

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette PMM2 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Attributs du produit: PMM2, 1-246aa, Human, His tag, E.coli

Pureté: > 95 % by SDS – PAGE

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol, 1mM DTT, 0.1M NaCl.

Stock: 4 °C

Détail du antigène

Antigène: PMM2 (Phosphomannomutase 2 (PMM2))

Autre désignation: PMM2 (PMM2 Produits)

Synonymes: cb626 Protein, zgc:56149 Protein, MGC82869 Protein, pmm2 Protein, CDG1 Protein, CDG1a Protein, CDGS Protein, PMI Protein, PMI1 Protein, PMM 2 Protein, AI585868 Protein, C86848 Protein, phosphomannomutase 2 Protein, phosphomannomutase 2 S homeolog Protein, pmm2 Protein, PMM2 Protein, pmm2.S Protein, PTRG_02815 Protein, Tsp_00480 Protein, Pmm2 Protein

Sujet: PMM2, also known as Phosphomannomutase 2, belongs to the eukaryotic PMM family. PMM2 is involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions. It catalyzes the isomerization of mannose 6-phosphate to mannose 1-phosphate. Mutations in PMM2 are associated with Congenital disorders of glycosylation (CDG)-Ia, an autosomal recessive disorder characterized by central nervous system dysfunction and multiorgan failure. Recombinant human PMM2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: CDG1, CDG1a, CDGS, Phosphomannomutase 2. NCBI no.: NP_000294

Poids moléculaire: 30.2 kDa (266aa), confirmed by MALDI-TOF