UBE2D2 Protein (AA 1-147) (His tag)

N° du produit ABIN667507

Détail du produit

Antigène: UBE2D2 (Ubiquitin-Conjugating Enzyme E2D 2 (UBE2D2))

Type de proteíne: Recombinant

Attributs du protein: AA 1-147

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette UBE2D2 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Attributs du produit: UBE2D2, 1-147aa, Human, His tag, E.coli

Pureté: > 95 % by SDS - PAGE

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol, 1mM DTT, 0.1M NaCl.

Stock: 4 °C

Détail du antigène

Antigène: UBE2D2 (Ubiquitin-Conjugating Enzyme E2D 2 (UBE2D2))

Autre désignation: UBE2D2 (UBE2D2 Produits)

Synonymes: E2(17)KB2 Protein, PUBC1 Protein, UBC4 Protein, UBC4/5 Protein, UBCH5B Protein, 1500034D03Rik Protein, Ubc2e Protein, Ube2d2 Protein, ubc4 Protein, ube2d2 Protein, zgc:55886 Protein, E217kB Protein, ubiquitin conjugating enzyme E2 D2 Protein, ubiquitin-conjugating enzyme E2D 2A Protein, ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast) Protein, ubiquitin-conjugating enzyme E2D 2 Protein, ubiquitin conjugating enzyme E2 D3 Protein, UBE2D2 Protein, Ube2d2a Protein, ube2d2 Protein, Ube2d2 Protein, UBE2D3 Protein

Sujet: UBE2D2 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase. UBE2D2 catalyzes ubiquitination of IkB-alpha in a phosphorylation and SCFB-TRCP dependent manner. Recombinant human UBE2D2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Ubiquitin-conjugating enzyme E2 D2, E2(17)KB2, PUBC1, UBC4, UBC4/5, UBCH5B. NCBI no.: NP_003330

Poids moléculaire: 18.9 kDa (167aa), confirmed by MALDI-TOF

Pathways: Activation of Innate immune Response, Toll-Like Receptors Cascades