HAO1 Protein (AA 1-370) (His tag)

N° du produit ABIN667522

Détail du produit

Antigène: HAO1 (Hydroxyacid Oxidase (Glycolate Oxidase) 1 (HAO1))

Type de proteíne: Recombinant

Attributs du protein: AA 1-370

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette HAO1 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Attributs du produit: HAO1, 1-370aa, Human, His tag, E.coli

Pureté: > 95 % by SDS - PAGE

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/ml (determined by Bradford assay)

Buffer: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 0.5M NaCl

Stock: 4 °C

Détail du antigène

Antigène: HAO1 (Hydroxyacid Oxidase (Glycolate Oxidase) 1 (HAO1))

Autre désignation: HAO1 (HAO1 Produits)

Synonymes: hao1 Protein, GOX Protein, GOX1 Protein, HAOX1 Protein, Gox1 Protein, XDH1 Protein, Hao-1 Protein, hydroxyacid oxidase 1 Protein, hydroxyacid oxidase (glycolate oxidase) 1 Protein, hydroxyacid oxidase (glycolate oxidase) 1 L homeolog Protein, hydroxyacid oxidase 1, liver Protein, CpipJ_CPIJ013711 Protein, THEYE_A0075 Protein, hao1 Protein, HAO1 Protein, hao1.L Protein, Hao1 Protein

Sujet: HAO1, also known as glycolate oxidase, is a member of the superfamily of the alpha hydroxy acid oxidases(HAO) enzymes. It catalyzes the FMN mediated oxidation of glycolate to glyoxylate and glyoxylate to oxalate with reduction of oxygen to hydrogen peroxide. It is most highly expressed in liver and pancreas and is most active on twocarbon substrates such as glycolate. Recently, it has been identified as a major contributor to hyperoxaluria, a disorder in which large deposits of calcium oxalate form kidney stones. Recombinant human HAO1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: Hydroxyacid oxidase 1, GOX (glycolate oxidase), GOX1, HAOX1. NCBI no.: NP_060015

Poids moléculaire: 45.0 kDa(406aa), confirmed by MALDI-TOF

Pathways: Monocarboxylic Acid Catabolic Process