IDH1 Protein (AA 1-414) (His tag)

N° du produit ABIN667603

Détail du produit

Antigène: IDH1 (Isocitrate Dehydrogenase 1 (NADP+), Soluble (IDH1))

Type de proteíne: Recombinant

Attributs du protein: AA 1-414

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette IDH1 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Attributs du produit: IDH1, 1-414aa , Human, His tag, E.coli

Pureté: > 95 % by SDS - PAGE

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/ml (determined by Bradford assay)

Buffer: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 0.1M NaCl,1mM DTT,0.1mM PMSF

Stock: 4 °C

Détail du antigène

Antigène: IDH1 (Isocitrate Dehydrogenase 1 (NADP+), Soluble (IDH1))

Autre désignation: IDH1 (IDH1 Produits)

Synonymes: IDCD Protein, IDH Protein, IDP Protein, IDPC Protein, PICD Protein, NADP-CICDH Protein, AI314845 Protein, AI788952 Protein, E030024J03Rik Protein, Id-1 Protein, Idh-1 Protein, Idpc Protein, cb876 Protein, fm90e09 Protein, im:7143416 Protein, wu:fm90e09 Protein, F23E12.180 Protein, F23E12_180 Protein, IDH-I Protein, NAD+ DEPENDENT ISOCITRATE DEHYDROGENASE SUBUNIT 1 Protein, isocitrate dehydrogenase 1 Protein, isocitrate dehydrogenase I Protein, isocitrate dehydrogenase (NADP(+)) 1, cytosolic Protein, isocitrate dehydrogenase 1 (NADP+), soluble Protein, isocitrate dehydrogenase 1 (NADP+) L homeolog Protein, isocitrate dehydrogenase 1 Protein, IDH1 Protein, Idh1 Protein, idh1.L Protein, idh1 Protein

Sujet: IDH1, also known as isocitrate dehydrogenase (IDHC) cytoplasmic enzyme, belongs to the isocitrate and isopropylmalate dehydrogenases family. This protein catalyzes the third step of the citric acid cycle, which involves the oxidative decarboxylation of isocitrate, forming alpha-ketoglutarate and CO2 in a two step reaction. The first step involves the oxidation of isocitrate to the intermediate oxalosuccinate, while the second step involves the production of alpha-ketoglutarate. Recombinant human IDH1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: Isocitrate dehydrogenase [NADP] cytoplasmic, IDCD, IDH, IDP, IDPC, PICD. NCBI no.: NP_005887

Poids moléculaire: 48.8 kDa (434aa), confirmed by MALDI-TOF

Pathways: L'effet Warburg