Cyclin D2 Protein (CCND2) (AA 1-289) (His tag)

N° du produit ABIN667637

Détail du produit

Antigène: Cyclin D2 (CCND2)

Type de proteíne: Recombinant

Attributs du protein: AA 1-289

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette Cyclin D2 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Attributs du produit: CCND2, 1-289 aa , Human, His tag, E.coli

Pureté: > 85 % by SDS - PAGE

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford)

Buffer: Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol, 2mM DTT, 1M Urea.

Stock: 4 °C

Détail du antigène

Antigène: Cyclin D2 (CCND2)

Autre désignation: CCND2 (CCND2 Produits)

Synonymes: si:ch211-240j22.2 Protein, ccnd2 Protein, CCND2 Protein, kiak0002 Protein, zgc:162280 Protein, LOC100224096 Protein, KIAK0002 Protein, BF642806 Protein, C86853 Protein, Vin-1 Protein, Vin1 Protein, cD2 Protein, 2600016F06Rik Protein, AI256817 Protein, cyclin D2, b Protein, cyclin D2 S homeolog Protein, cyclin D2 Protein, G1/S-specific cyclin-D2 Protein, cyclin D2, a Protein, cyclin D2 L homeolog Protein, ccnd2b Protein, ccnd2.S Protein, CCND2 Protein, ccnd2 Protein, ccnd2a Protein, Ccnd2 Protein, ccnd2.L Protein

Sujet: CCND2 belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. High level expression of this protein was observed in ovarian and testicular tumors. Recombinant human CCND2 protein, fused to His-tag at N-terminus, was expressed in E.coli. Synonyms: Cyclin D2, KIAK0002, MGC102758, G1/S-specific cyclin-D2. NCBI no.: NP_001750

Poids moléculaire: 35.6 kDa (313aa)

Pathways: Cycle Cellulaire, Mitotic G1-G1/S Phases