COMMD1 Protein (AA 1-190) (His tag)

N° du produit ABIN667798

Détail du produit

Antigène: COMMD1 (Copper Metabolism (Murr1) Domain Containing 1 (COMMD1))

Type de proteíne: Recombinant

Attributs du protein: AA 1-190

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette COMMD1 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Attributs du produit: COMMD1, 1-190aa, Human, His tag, E.coli

Pureté: > 90 % by SDS - PAGE

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/ml (determined by Bradford assay)

Buffer: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol 0.1M NaCl

Stock: 4 °C

Détail du antigène

Antigène: COMMD1 (Copper Metabolism (Murr1) Domain Containing 1 (COMMD1))

Autre désignation: COMMD1 (COMMD1 Produits)

Synonymes: C2orf5 Protein, MURR1 Protein, murr1 Protein, commd1 Protein, si:ch211-213b8.2 Protein, DDBDRAFT_0184206 Protein, DDBDRAFT_0266452 Protein, DDB_0184206 Protein, DDB_0266452 Protein, COMMD1 Protein, MGC114682 Protein, AI256843 Protein, Murr1 Protein, U2/Mu Protein, copper metabolism domain containing 1 Protein, copper metabolism (Murr1) domain containing 1 Protein, COMM domain-containing protein 1 Protein, copper metabolism domain containing 1 L homeolog Protein, COMM domain containing 1 Protein, COMMD1 Protein, commd1 Protein, comd1 Protein, Commd1 Protein, commd1.L Protein

Sujet: COMMD1, also known as copper metabolism MURR1 domain-containing protein 1, is a 190 amino acid protein responsible for inhibition of TNF-induced NFkB p50 and has a suggested role in facilitation of biliary copper excretion within hepatocytes. High expression is found in liver tissue, with lower expressions in lung, heart, kidney and brain tissue. This protein interacts directly with COMMD6 and ATP7B, and indirectly with IkB-beta and COMMD7. Recombinant human COMMD1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: C2orf5, MURR1, COMM domain-containing protein 1, COMMD-1, COMMD 1, COMM, MURR 1, MURR-1. NCBI no.: NP_689729

Poids moléculaire: 23.3 kDa (210aa), confirmed by MALDI-TOF

Pathways: Transition Metal Ion Homeostasis