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LAMTOR2 Protein (AA 1-125) (His tag)
LAMTOR2
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
> 95 % by SDS - PAGE
SDS
Détail du produit
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Antigène
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LAMTOR2
(Late Endosomal/lysosomal Adaptor, MAPK and mTOR Activator 2 (LAMTOR2))
Type de proteíne
Recombinant
Attributs du protein
AA 1-125
Origine
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Humain
Source
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Escherichia coli (E. coli)
Purification/Conjugué
Cette LAMTOR2 protéine est marqué à la His tag.
Application
SDS-PAGE (SDS)
Attributs du produit
ROBLD3, 1-125aa, Human, His tag, E.coli
Pureté
> 95 % by SDS - PAGE
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Information d'application
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Restrictions
For Research Use only
Stockage
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Format
Liquid
Concentration
1 mg/ml (determined by Bradford assay)
Buffer
Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 0.2M Nacl, 2mM DTT, 10% glycerol
Stock
4 °C
Détail du antigène
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Antigène
LAMTOR2
(Late Endosomal/lysosomal Adaptor, MAPK and mTOR Activator 2 (LAMTOR2))
Autre désignation
ROBLD3 (LAMTOR2 Produits )
Synonymes
ENDAP Protein, HSPC003 Protein, MAPBPIP Protein, MAPKSP1AP Protein, ROBLD3 Protein, Ragulator2 Protein, p14 Protein, 2010111E04Rik Protein, AL022628 Protein, Mapbpip Protein, P14 Protein, Rab25 Protein, Robld3 Protein, RGD1562501 Protein, cg5189 Protein, endap Protein, hspc003 Protein, mapbpip Protein, mapbpip-B Protein, mapksp1ap Protein, ragulator2 Protein, robld3 Protein, robld3-b Protein, zgc:100811 Protein, lamtor2 Protein, lamtor2-a Protein, lamtor2-b Protein, mapbpip-A Protein, robld3-a Protein, late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 Protein, late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 S homeolog Protein, late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 L homeolog Protein, LAMTOR2 Protein, Lamtor2 Protein, lamtor2.S Protein, lamtor2 Protein, lamtor2.L Protein
Sujet
ROBLD3, also known as MAPBPIP, belongs to the GAMAD family. It is an adapter protein that enhances the efficiency of the MAP kinase cascade and facilitates the activation of MAPK2. ROBLD3 compels the recruitment of MP1 to late endosomes where they form a very stable heterodimeric complex required for ERK activation on endosomes. Recombinant human ROBLD3 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Mitogen-activated protein-binding protein-interacting protein, ENDAP, HSPC003, MAPBPIP, MAPKSP1AP, p14. NCBI no.: NP_054736
Poids moléculaire
16.0 kDa (149aa), confirmed by MALDI-TOF
Pathways
Signalisation PI3K-Akt
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