WHSC2 Protein (AA 1-539) (His tag)

N° du produit ABIN667859

Détail du produit

Antigène: WHSC2 (Wolf-Hirschhorn Syndrome Candidate 2 (WHSC2))

Type de proteíne: Recombinant

Attributs du protein: AA 1-539

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette WHSC2 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Attributs du produit: WHSC2, 1-539aa, Human, His tag, E.coli

Pureté: > 85 % by SDS - PAGE

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 0.2M NaCl, 5mM DTT, 1mM EDTA, 20% glycerol

Stock: 4 °C

Détail du antigène

Antigène: WHSC2 (Wolf-Hirschhorn Syndrome Candidate 2 (WHSC2))

Autre désignation: WHSC2 (WHSC2 Produits)

Synonymes: BcDNA:SD07139 Protein, CG5874 Protein, Dmel\\CG5874 Protein, NELF Protein, NELF-A Protein, Whsc2 Protein, fi75f03 Protein, whsc2 Protein, wu:fi75f03 Protein, MGC85474 Protein, WHSC2 Protein, nelfa Protein, nelf-a Protein, p/okcl.15 Protein, Whsc2h Protein, Negative elongation factor A Protein, negative elongation factor complex member A Protein, negative elongation factor complex member A L homeolog Protein, negative elongation factor complex member A, Whsc2 Protein, Nelf-A Protein, Nelfa Protein, nelfa Protein, nelfa.L Protein, NELFA Protein

Sujet: WHSC2, also known as NELF-A, is a protein factor required for DRB-sensitive transcription. This protein is one of the five components of the multisubunit NELF complex that cooperates with DSIF to repress RNA polymerase II elongation. Wolf-Hirschhorn syndrome is a multiple malformation syndrome characterized by mental and developmental defects resulting from a hemizygous deletion of the distal short arm of chromosome 4 (4p16.3). Recombinant human WHSC2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Wolf-Hirschhorn syndrome candidate 2, NELF-A, NELFA, P/OKcl.15, Negative elongation factor A. NCBI no.: NP_005654

Poids moléculaire: 60.6 kDa (559aa)

Pathways: Chromatin Binding