CDK2 Protein (AA 1-298) (His tag)

N° du produit ABIN667950

Détail du produit

Antigène: CDK2 (Cyclin-Dependent Kinase 2 (CDK2))

Type de proteíne: Recombinant

Attributs du protein: AA 1-298

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette CDK2 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Attributs du produit: CDK2, 1-298aa, Human, His tag, E.coli

Pureté: > 95 % by SDS - PAGE

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/ml (determined by Bradford assay)

Buffer: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 1mM DTT

Stock: 4 °C

Détail du antigène

Antigène: CDK2 (Cyclin-Dependent Kinase 2 (CDK2))

Autre désignation: CDK2 (CDK2 Produits)

Synonymes: p33(CDK2) Protein, A630093N05Rik Protein, wu:fa10c02 Protein, zgc:56598 Protein, zgc:77684 Protein, eg1 Protein, CDKN2 Protein, cdk2L Protein, cyclin dependent kinase 2 Protein, cyclin-dependent kinase 2 Protein, cyclin-dependent kinase 2 S homeolog Protein, CDK2 Protein, Cdk2 Protein, cdk2 Protein, cdk2.S Protein

Sujet: CDK2, also known as cyclin-depentent kinase 2, is a member of the Ser/Thr protein kinase family. It is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and is essential for cell cycle G1/S phase transition. This protein associates with and is regulated by the regulatory subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). Its activity is also regulated by protein phosphorylation. Recombinant human CDK2 protein, fused to His-tag at C-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: Cyclin-depentent kinase 2, p33, CDK2. NCBI no.: NP_001789

Poids moléculaire: 35.0 kDa (306aa), confirmed by MALDI-TOF

Pathways: Signalisation PI3K-Akt, Cycle Cellulaire, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA