LDLRAP1 Protein (AA 1-308) (His tag)

N° du produit ABIN668020

Détail du produit

Antigène: LDLRAP1 (Low Density Lipoprotein Receptor Adaptor Protein 1 (LDLRAP1))

Type de proteíne: Recombinant

Attributs du protein: AA 1-308

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette LDLRAP1 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Attributs du produit: LDLRAP1, 1-308aa, Human, His tag, E.coli

Pureté: > 90 % by SDS - PAGE

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 2mM DTT, 10% glycerol, 200mM NaCl

Stock: 4 °C

Détail du antigène

Antigène: LDLRAP1 (Low Density Lipoprotein Receptor Adaptor Protein 1 (LDLRAP1))

Autre désignation: LDLRAP1 (LDLRAP1 Produits)

Synonymes: ARH Protein, ARH1 Protein, ARH2 Protein, FHCB1 Protein, FHCB2 Protein, AA691260 Protein, Arh Protein, Arh1 Protein, RGD1563417 Protein, arh Protein, arh1 Protein, arh2 Protein, fhcb1 Protein, fhcb2 Protein, xptb Protein, LDLRAP1 Protein, ldlrap1 Protein, sb:cb50 Protein, zgc:56121 Protein, zgc:158745 Protein, low density lipoprotein receptor adaptor protein 1 Protein, low density lipoprotein receptor adaptor protein 1 L homeolog Protein, low density lipoprotein receptor adaptor protein 1 S homeolog Protein, low density lipoprotein receptor adaptor protein 1a Protein, low density lipoprotein receptor adaptor protein 1b Protein, LDLRAP1 Protein, Ldlrap1 Protein, ldlrap1 Protein, ldlrap1.L Protein, ldlrap1.S Protein, ldlrap1a Protein, ldlrap1b Protein

Sujet: LDLRAP1 (Low density lipoprotein receptor adapter protein 1) is a cytosolic protein which contains a phosphotyrosine binding (PTD) domain. LDLRAP1 is a cytosolic adaptor that couples LDLR to endocytic machinery. Defects in LDLRAP1 are the cause of autosomal recessive hypercholesterolemia (ARH). ARH is a disorder caused by defective internalization of LDL receptors (LDLR) in the liver. Recombinant human LDLRAP1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Low density lipoprotein receptor adaptor protein 1, ARH, ARH1, ARH2, FHCB1, FHCB2. NCBI no.: AAH29770

Poids moléculaire: 36.1kDa (328aa), confirmed by MALDI-TOF

Pathways: Lipid Metabolism