BID Protein (AA 1-195)

N° du produit ABIN668038

Détail du produit

Antigène: BID (BH3 Interacting Domain Death Agonist (BID))

Type de proteíne: Recombinant

Attributs du protein: AA 1-195

Origine: Humain

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Attributs du produit: BID, 1-195aa, Human, Recombinant, E.coli

Pureté: > 95 % by SDS - PAGE

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid in 20 mM Tris-HCl pH 8.0, 20% glycerol.

Stock: 4 °C

Détail du antigène

Antigène: BID (BH3 Interacting Domain Death Agonist (BID))

Autre désignation: BID (BID Produits)

Synonymes: FP497 Protein, 2700049M22Rik Protein, AI875481 Protein, AU022477 Protein, BID Protein, bid Protein, si:ch211-238n5.6 Protein, fp497 Protein, xbid Protein, DKFZp469E066 Protein, BH3 interacting domain death agonist Protein, BH3 interacting domain death agonist S homeolog Protein, BID Protein, Bid Protein, bida Protein, bid.S Protein, bid Protein

Sujet: BID is a pro-apoptotic Bcl-2 protein containing only the BH3 domain. In response to apoptotic signaling, BID interacts with another Bcl-2 family protein, Bax, leading to the insertion of Bax into the outer mitochondrial membrane. Bax is believed to induce the opening of the mitochondrial voltage-dependent anion channel. This results in the release of cytochrome c and other pro-apoptotic factors from the mitochondria leading to activation of caspases. Recombinant BID protein was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: FP497, MGC15319, MGC42355, BH3 interacting domain death agonist isoform 2, BID, BH3 interacting domain death agonist isoform 2 Apoptotic death agonist, Apoptotic death agonist BID, BH3 interacting domain death agonist, HGNC:1050, BH3 interacting domain death agonist p11, BH3 interacting domain death agonist p13, BH3 interacting domain death agonist p15, BID isoform ES(1b), BID isoform L(2), Desmocollin type 4, Human BID coding sequence, OTTHUMP00000196197, p11 BID, p13 BID, p15 BID, p22 BID. NCBI no.: NP_001187

Poids moléculaire: 21.9 kDa (195 aa), confirmed by MALDI-TOF.

Pathways: Apoptose, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity