IL15RA Protein (AA 31-205) (Fc Tag)
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- Antigène Voir toutes IL15RA Protéines
- IL15RA (Interleukin 15 Receptor, alpha (IL15RA))
- Type de proteíne
- Recombinant
- Activité biologique
- Active
- Attributs du protein
- AA 31-205
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette IL15RA protéine est marqué à la Fc Tag.
- Séquence
- AA 31-205
- Pureté
- >95 % as determined by SDS-PAGE.
- niveau d'endotoxine
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product IL15RA Protéine
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Tris with Glycine, Arginine and NaCl, pH 7.5
- Conseil sur la manipulation
- Please avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
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- Antigène
- IL15RA (Interleukin 15 Receptor, alpha (IL15RA))
- Autre désignation
- IL-15 R alpha (IL15RA Produits)
- Synonymes
- IL15RA Protein, CD215 Protein, AA690181 Protein, IL-15RA Protein, interleukin 15 receptor subunit alpha Protein, interleukin 15 receptor, alpha chain Protein, IL15RA Protein, Il15ra Protein
- Sujet
- IL15R is a heterotrimer of IL15RA, IL2RB and IL2RG. IL-15RA, also known as CD215, IL-15 R alpha, is a widely expressed 60 kDa transmembrane glycoprotein. High-affinity receptor for interleukin-15. Can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells. Expression of different isoforms may alter or interfere with signal transduction. An interleukin (IL)-15 superagonist/IL-15 receptor α fusion complex (IL-15SA/IL-15RA, ALT-803) activates the IL-15 receptor on CD8 T cells and NK cells, and has shown significant anti-tumor. Signal transduction involves SYK. Higher levels of soluble sIL-15RA form in comparison with membrane-bound forms is present in all brain structures.
- Poids moléculaire
- 44.8 kDa
- NCBI Accession
- NP_002180
- Pathways
- Signalistation JAK/STAT
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