ICOS Protein (AA 21-144) (Fc Tag)
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- Antigène Voir toutes ICOS Protéines
- ICOS (Inducible T-Cell Co-Stimulator (ICOS))
- Type de proteíne
- Recombinant
- Activité biologique
- Active
- Attributs du protein
- AA 21-144
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Origine
- Souris
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette ICOS protéine est marqué à la Fc Tag.
- Pureté
- >95 % as determined by SDS-PAGE.
- niveau d'endotoxine
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product ICOS Protéine
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Tris with Glycine, Arginine and NaCl, pH 7.5
- Stock
- -20 °C
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- Antigène
- ICOS (Inducible T-Cell Co-Stimulator (ICOS))
- Autre désignation
- ICOS (ICOS Produits)
- Synonymes
- ICOS Protein, AILIM Protein, CCLP Protein, CRP-1 Protein, H4 Protein, Ly115 Protein, CD278 Protein, CVID1 Protein, Ailim Protein, inducible T-cell costimulator Protein, inducible T cell co-stimulator Protein, inducible T-cell co-stimulator Protein, ICOS Protein, LOC100232284 Protein, Icos Protein
- Sujet
- Inducible T-cell costimulator (ICOS) is also known as Activation-inducible lymphocyte immunomediatory molecule (AILIM), CD278, which belongs to the CD28 family of immune costimulatory receptors consisting of CD28, CTLA-4 and PD-1. ICOS enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. CD278 / ICOS prevents the apoptosis of pre-activated T-cells and also plays a critical role in CD40-mediated class switching of immunoglobin isotypes.
- Poids moléculaire
- 40.6 kDa
- Pathways
- Cancer Immune Checkpoints
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