ROR2 Protein (His tag)

N° du produit ABIN6964076

Détail du produit

Antigène: ROR2 (Receptor Tyrosine Kinase-Like Orphan Receptor 2 (ROR2))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette ROR2 protéine est marqué à la His tag.

Fonction: Recombinant human ROR2 Protein with C-terminal 6xHis tag

Specificité: ROR2 (Glu34-Gly403) 6xHis tag

Attributs du produit: Extracellular Domain Protein

Purification: affinity purification

Pureté: The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstitute with deionized water

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Agent conservateur: Without preservative

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Date de péremption: 12 months

Détail du antigène

Antigène: ROR2 (Receptor Tyrosine Kinase-Like Orphan Receptor 2 (ROR2))

Autre désignation: ROR2 (ROR2 Produits)

Synonymes: BDB Protein, BDB1 Protein, NTRKR2 Protein, Ntrkr2 Protein, mRor2 Protein, ROR2 Protein, bdb Protein, bdb1 Protein, Xror2 Protein, ntrkr2 Protein, MGC97773 Protein, LOC100219935 Protein, ror2 Protein, xror2 Protein, receptor tyrosine kinase like orphan receptor 2 Protein, receptor tyrosine kinase-like orphan receptor 2 Protein, receptor tyrosine kinase like orphan receptor 2 L homeolog Protein, ROR2 Protein, Ror2 Protein, ror2 Protein, ror2.L Protein

Sujet: Synonymes: ROR2,NTRKR2
Description: The protein encoded by this gene is a receptor protein tyrosine kinase and type I transmembrane protein that belongs to the ROR subfamily of cell surface receptors. The protein may be involved in the early formation of the chondrocytes and may be required for cartilage and growth plate development. Mutations in this gene can cause brachydactyly type B, a skeletal disorder characterized by hypoplasia/aplasia of distal phalanges and nails. In addition, mutations in this gene can cause the autosomal recessive form of Robinow syndrome, which is characterized by skeletal dysplasia with generalized limb bone shortening, segmental defects of the spine, brachydactyly, and a dysmorphic facial appearance.

Poids moléculaire: predicted molecular mass of 42.2 kDa after removal of the signal peptide.The apparent molecular mass of ROR2-His is 55-70 kDa due to glycosylation.

ID gène: 4920

UniProt: Q01974

Pathways: Signalisation RTK, Signalisation WNT