MST1R Protein (Fc Tag)

N° du produit ABIN6964141

Détail du produit

Antigène: MST1R (Macrophage Stimulating 1 Receptor (C-Met-Related tyrosine Kinase) (MST1R))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette MST1R protéine est marqué à la Fc Tag.

Fonction: Recombinant Human MST1R Protein with C-terminal Human Fc tag

Specificité: MST1R (Glu25-Thr957) hFc (Glu99-Ala330)

Attributs du produit: Extracellular Domain Protein

Purification: affinity purification

Pureté: The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstitute with deionized water

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Agent conservateur: Without preservative

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Date de péremption: 12 months

Détail du antigène

Antigène: MST1R (Macrophage Stimulating 1 Receptor (C-Met-Related tyrosine Kinase) (MST1R))

Autre désignation: MST1R (MST1R Produits)

Synonymes: CD136 Protein, CDw136 Protein, PTK8 Protein, RON Protein, Fv-2 Protein, Fv2 Protein, Ron Protein, STK Protein, Cdw136 Protein, Ptk8 Protein, Stk Protein, macrophage stimulating 1 receptor Protein, macrophage stimulating 1 receptor (c-met-related tyrosine kinase) Protein, MST1R Protein, Mst1r Protein

Sujet: Synonymes: CD136, CDw136, NPCA3, PTK8, RON
Description: This gene encodes a cell surface receptor for macrophage-stimulating protein (MSP) with tyrosine kinase activity. The mature form of this protein is a heterodimer of disulfide-linked alpha and beta subunits, generated by proteolytic cleavage of a single-chain precursor. The beta subunit undergoes tyrosine phosphorylation upon stimulation by MSP. This protein is expressed on the ciliated epithelia of the mucociliary transport apparatus of the lung, and together with MSP, thought to be involved in host defense. Alternative splicing generates multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing.

Poids moléculaire: predicted molecular mass of 125.9 kDa after removal of the signal peptide. The apparent molecular mass of MST1R-hFc is 130-250 kDa due to glycosylation.

UniProt: Q04912

Pathways: Signalisation RTK