PVRL4 Protein (His tag)

N° du produit ABIN6964194

Détail du produit

Antigène: PVRL4 (Poliovirus Receptor-Related 4 (PVRL4))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette PVRL4 protéine est marqué à la His tag.

Fonction: Recombinant human NECTIN-4 protein with C-terminal 6xHis tag

Specificité: NECTIN-4 (Gly32-Ser349) 6xHis Tag

Attributs du produit: Extracellular Domain Protein

Purification: affinity purification

Pureté: The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstitute with deionized water

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Agent conservateur: Without preservative

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Date de péremption: 12 months

Détail du antigène

Antigène: PVRL4 (Poliovirus Receptor-Related 4 (PVRL4))

Autre désignation: Nectin-4 (PVRL4 Produits)

Synonymes: PVRL4 Protein, si:ch211-155e24.1 Protein, 1200017F15Rik Protein, Prr4 Protein, RGD1559826 Protein, EDSS1 Protein, LNIR Protein, PRR4 Protein, nectin-4 Protein, nectin cell adhesion molecule 4 Protein, NECTIN4 Protein, nectin4 Protein, Nectin4 Protein

Sujet: Synonymes: EDSS1, LNIR, nectin-4, PRR4, PVRL4
Description: This gene encodes a member of the nectin family. The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain. It is involved in cell adhesion through trans-homophilic and -heterophilic interactions. It is a single-pass type I membrane protein. The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17/TACE. The secreted form is found in both breast tumor cell lines and breast tumor patients. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder. Alternatively spliced transcript variants have been found but the full-length nature of the variant has not been determined.

Poids moléculaire: predicted molecular mass of 34.9 kDa after removal of the signal peptide.The apparent molecular mass of NECTIN-4-His is 35-55 kDa due to glycosylation.

UniProt: Q96NY8

Pathways: Cell-Cell Junction Organization