IL11RA Protein (Fc Tag)

N° du produit ABIN7092738

Détail du produit

Antigène: IL11RA (Interleukin 11 Receptor, alpha (IL11RA))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette IL11RA protéine est marqué à la Fc Tag.

Fonction: Recombinant Human IL11RA with C-terminal human Fc tag

Specificité: IL11RA (Ser24-Ala370) hFc (Glu99-Ala330)

Attributs du produit: Extracellular Domain Protein

Purification: affinity purification

Pureté: The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstitute with deionized water

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Date de péremption: 12 months

Détail du antigène

Antigène: IL11RA (Interleukin 11 Receptor, alpha (IL11RA))

Autre désignation: IL11RA (IL11RA Produits)

Synonymes: CRSDA Protein, fi26e06 Protein, il-11ra Protein, wu:fi26e06 Protein, AI314697 Protein, GP130 Protein, Il-11ra Protein, Il11ra Protein, Il11ra2 Protein, NR1 Protein, interleukin 11 receptor subunit alpha Protein, interleukin 11 receptor, alpha Protein, interleukin 11 receptor subunit alpha 1 Protein, interleukin 11 receptor, alpha chain 1 Protein, IL11RA Protein, il11ra Protein, Il11ra1 Protein, Il11ra Protein

Sujet: Synonymes: IL-11 R alpha,IL-11 RA,IL11RA,Interleukin-11 receptor subunit alpha,IL-11 receptor subunit alpha,IL-11R subunit alpha,IL-11R-alpha
Description: Interleukin 11 is a stromal cell-derived cytokine that belongs to a family of pleiotropic and redundant cytokines that use the gp130 transducing subunit in their high affinity receptors. This gene encodes the IL-11 receptor, which is a member of the hematopoietic cytokine receptor family. This particular receptor is very similar to ciliary neurotrophic factor, since both contain an extracellular region with a 2-domain structure composed of an immunoglobulin-like domain and a cytokine receptor-like domain. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2012]

Poids moléculaire: predicted molecular mass of 44.3 kDa after removal of the signal peptide.The apparent molecular mass of IL11RA-hFc is 35-55 kDa due to glycosylation.

UniProt: Q14626

Pathways: Signalistation JAK/STAT, Growth Factor Binding