FGF19 Protein (AA 25-216) (Fc Tag)

N° du produit ABIN7012994

Détail du produit

Antigène: FGF19 (Fibroblast Growth Factor 19 (FGF19))

Type de proteíne: Recombinant

Attributs du protein: AA 25-216

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette FGF19 protéine est marqué à la Fc Tag.

Fonction: Human FGF19 Protein, Fc Tag

Pureté: >90 % as determined by SDS-PAGE.

niveau d'endotoxine: Less than 1.0 EU per μg by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH 7.5

Stock: -20 °C

Détail du antigène

Antigène: FGF19 (Fibroblast Growth Factor 19 (FGF19))

Autre désignation: FGF19 (FGF19 Produits)

Synonymes: FGF-19 Protein, Fgf15 Protein, fibroblast growth factor 19 Protein, FGF19 Protein, Fgf19 Protein, fgf19 Protein

Sujet: Fibroblast growth factor (FGF)19 is the first members of a new subfamily of FGFs and could act as hormones. During fetal life, FGF15/19 is involved in organogenesis, affecting the development of the ear, eye, heart, and brain. FGFs-FGFRs are involved in regulation of many biological processes such as embryonic development, cell proliferation, differentiation, and tissue repair. The dysregulation of FGF-FGFR was observed in different types of diseases, disorders, and cancers. Notably, aberrant expression of FGF19/FGFR4 contributes to Hepatocellular Carcinoma progression.

Poids moléculaire: 47.9 kDa

Pathways: Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway