IL-2 R beta & IL-2 R alpha & IL-2 R gamma (AA 27-239) (Active) protein (His tag,Twin-Strep tag)

N° du produit ABIN7013080

Détail du produit

Antigène: IL-2 R beta & IL-2 R alpha & IL-2 R gamma

Type de proteíne: Recombinant

Activité biologique: Active

Attributs du protein: AA 27-239

Origine: Rat

Source: HEK-293 Cells

Purification/Conjugué: His tag,Twin-Strep tag

Fonction: Rat IL-2 R beta&IL-2 R alpha&IL-2 R gamma Protein, His Tag&Twin-Strep Tag (MALS verified)

Pureté: >95 % as determined by reduced SDS-PAGE.

niveau d'endotoxine: Less than 1.0 EU per μg by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: PBS, pH 7.4

Stock: -20 °C

Détail du antigène

Antigène: IL-2 R beta & IL-2 R alpha & IL-2 R gamma

Sujet: Both Interleukin-2 receptor subunit beta and Interleukin-2 receptor subunit gamma are receptor for interleukin-2. Common subunit for the receptors for a variety of interleukins. Interacts with SHB upon interleukin stimulation. Probably in association with IL15RA, involved in the stimulation of neutrophil phagocytosis by IL15. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. IL2R exists in 3 different forms: a high affinity dimer, an intermediate affinity monomer (beta subunit), and a low affinity monomer (alpha subunit). The high and intermediate affinity forms also associate with a gamma subunit.

Poids moléculaire: 30.2 kDa & 59.3 kDa