IL-2 R beta & IL-2 R alpha & IL-2 R gamma (AA 22-212), (AA 23-254), (AA 27-239) (Active) protein (Fc Tag)

N° du produit ABIN7013610

Détail du produit

Antigène: IL-2 R beta & IL-2 R alpha & IL-2 R gamma

Type de proteíne: Recombinant

Activité biologique: Active

Attributs du protein: AA 22-212, AA 23-254, AA 27-239

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Fc Tag

Attributs du produit: Human IL-2 R beta&IL-2 R alpha&IL-2 R gamma Protein, Fc Tag&Fc Tag (MALS verified)

Pureté: >95 % as determined by SDS-PAGE.

niveau d'endotoxine: Less than 1.0 EU per μg by the LAL method.

Information d'application

Indications d'application: MALS verified

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: PBS, pH 7.4

Stock: -20 °C

Détail du antigène

Antigène: IL-2 R beta & IL-2 R alpha & IL-2 R gamma

Sub Type: Cocktail

Sujet: Both Interleukin-2 receptor subunit beta and Interleukin-2 receptor subunit gamma are receptor for interleukin-2. Common subunit for the receptors for a variety of interleukins. Interacts with SHB upon interleukin stimulation. Probably in association with IL15RA, involved in the stimulation of neutrophil phagocytosis by IL15. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. IL2R exists in 3 different forms: a high affinity dimer, an intermediate affinity monomer (beta subunit), and a low affinity monomer (alpha subunit). The high and intermediate affinity forms also associate with a gamma subunit.

Poids moléculaire: 51.1 kDa | 75.4 kDa