SARS-CoV-2 Spike Protein (B.1.617.2 - delta, RBD) (His tag)

N° du produit ABIN7013122

Détail du produit

Antigène: SARS-CoV-2 Spike

Type de proteíne: Recombinant

Activité biologique: Active

Attributs du protein: B.1.617.2 - delta, RBD

Origine: SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Delta

Source: HEK-293 Cells

Purification/Conjugué: Cette SARS-CoV-2 Spike protéine est marqué à la His tag.

Fonction: SARS-CoV-2 Spike RBD (L452R, T478K), His Tag (MALS verified)

Specificité: SARS-CoV-2 Spike RBD (L452R, T478K)

Attributs du produit: SARS-CoV-2 Spike RBD (L452R, T478K), His Tag is expressed from human 293 cells (HEK293). It contains AA Arg 319 - Lys 537 (Accession # QHD43416.1(L452R, T478K). The mutations (L452R, T478K) were identified in the SARS-CoV-2 variants which emerged in India (known as B.1.617.2).

Pureté: >90 % as determined by reduced SDS-PAGE.

niveau d'endotoxine: Less than 1.0 EU per μg by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: PBS, pH 7.4

Stock: -20 °C

Détail du antigène

Antigène: SARS-CoV-2 Spike

Abstract: SARS-CoV-2 Spike Produits

Synonymes: E2 Protein, E2 glycoprotein precursor Protein, Surface Glycoprotein Protein, S Protein

Classe de substances: Viral Protein

Sujet: It's been reported that SARS-CoV-2 can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

Poids moléculaire: 26.6 kDa

NCBI Accession: QHD43416